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DRUG:
Tepmetko (tepotinib)
i
Other names:
EMD-1214063, MSC-2156119J, MSC-2156119, MSC2156119, MSC2156119J, EMD1214063
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Associations
(24)
News
Trials
Company:
EMD Serono
Drug class:
c-MET inhibitor
Related drugs:
‹
savolitinib (29)
amivantamab-vmjw (25)
capmatinib (23)
TPX-0022 (8)
CKD-702 (6)
LY2801653 (6)
TQ-B3101 (6)
GB263T (5)
WXSH0011 (5)
SCC244 (5)
ARQ 197 (5)
REGN5093 (4)
MGCD265 (4)
AMG 102 (4)
MCLA-129 (3)
ABN401 (3)
TQ-B3139 (3)
BPI-9016M (2)
HQP8361 (2)
HS-10241 (2)
S95027 (2)
APL-101 (2)
AV-299 (2)
GSK1363089 (2)
DO-1 (1)
GST-HG16 (1)
JNJ-38877605 (1)
KRC-108 (1)
SGX523 (1)
SU11274 (1)
LY2875358 (1)
E7050 (1)
RG3638 (1)
AL2846 (0)
AMG 208 (0)
AMG 337 (0)
ARGX-111 (0)
ASKC202 (0)
ASLAN002 (0)
DO-2 (0)
EMD 1204831 (0)
HLX55 (0)
MRX34 (0)
PF-04217903 (0)
PHA665752 (0)
PM1080 (0)
RXDX-106 (0)
S-49076 (0)
SAIT301 (0)
SAR 125844 (0)
SPH 3348 (0)
TAVO412 (0)
DCC-2701 (0)
Ami-LC (0)
EMB-01 (0)
BMS-794833 (0)
h224G11 (0)
XL092 (0)
savolitinib (29)
amivantamab-vmjw (25)
capmatinib (23)
TPX-0022 (8)
CKD-702 (6)
LY2801653 (6)
TQ-B3101 (6)
GB263T (5)
WXSH0011 (5)
SCC244 (5)
ARQ 197 (5)
REGN5093 (4)
MGCD265 (4)
AMG 102 (4)
MCLA-129 (3)
ABN401 (3)
TQ-B3139 (3)
BPI-9016M (2)
HQP8361 (2)
HS-10241 (2)
S95027 (2)
APL-101 (2)
AV-299 (2)
GSK1363089 (2)
DO-1 (1)
GST-HG16 (1)
JNJ-38877605 (1)
KRC-108 (1)
SGX523 (1)
SU11274 (1)
LY2875358 (1)
E7050 (1)
RG3638 (1)
AL2846 (0)
AMG 208 (0)
AMG 337 (0)
ARGX-111 (0)
ASKC202 (0)
ASLAN002 (0)
DO-2 (0)
EMD 1204831 (0)
HLX55 (0)
MRX34 (0)
PF-04217903 (0)
PHA665752 (0)
PM1080 (0)
RXDX-106 (0)
S-49076 (0)
SAIT301 (0)
SAR 125844 (0)
SPH 3348 (0)
TAVO412 (0)
DCC-2701 (0)
Ami-LC (0)
EMB-01 (0)
BMS-794833 (0)
h224G11 (0)
XL092 (0)
›
Associations
(24)
News
Trials
VERI cancer hierarchy
Reset Filters
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
tepotinib
Sensitive: A1 - Approval
tepotinib
Sensitive
:
A1
tepotinib
Sensitive: A1 - Approval
tepotinib
Sensitive
:
A1
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
tepotinib
Sensitive: A2 - Guideline
tepotinib
Sensitive
:
A2
tepotinib
Sensitive: A2 - Guideline
tepotinib
Sensitive
:
A2
MET exon 14 mutation
Lung Adenocarcinoma
MET exon 14 mutation
Lung Adenocarcinoma
tepotinib
Sensitive: C1 - Off-label
tepotinib
Sensitive
:
C1
tepotinib
Sensitive: C1 - Off-label
tepotinib
Sensitive
:
C1
MET exon 14 mutation
Gastric Cancer
MET exon 14 mutation
Gastric Cancer
tepotinib
Sensitive: C1 - Off-label
tepotinib
Sensitive
:
C1
tepotinib
Sensitive: C1 - Off-label
tepotinib
Sensitive
:
C1
MET amplification
Lung Cancer
MET amplification
Lung Cancer
tepotinib
Sensitive: C2 – Inclusion Criteria
tepotinib
Sensitive
:
C2
tepotinib
Sensitive: C2 – Inclusion Criteria
tepotinib
Sensitive
:
C2
MET amplification
Gastric Cancer
MET amplification
Gastric Cancer
tepotinib
Sensitive: C2 – Inclusion Criteria
tepotinib
Sensitive
:
C2
tepotinib
Sensitive: C2 – Inclusion Criteria
tepotinib
Sensitive
:
C2
MET overexpression
Non Small Cell Lung Cancer
MET overexpression
Non Small Cell Lung Cancer
tepotinib
Sensitive: C2 – Inclusion Criteria
tepotinib
Sensitive
:
C2
tepotinib
Sensitive: C2 – Inclusion Criteria
tepotinib
Sensitive
:
C2
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
EGFR mutation + MET overexpression
Non Small Cell Lung Cancer
EGFR mutation + MET overexpression
Non Small Cell Lung Cancer
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
MET overexpression
Hepatocellular Cancer
MET overexpression
Hepatocellular Cancer
tepotinib
Sensitive: C3 – Early Trials
tepotinib
Sensitive
:
C3
tepotinib
Sensitive: C3 – Early Trials
tepotinib
Sensitive
:
C3
MET amplification
Non Small Cell Lung Cancer
MET amplification
Non Small Cell Lung Cancer
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
EGFR wild-type + MET amplification
Non Small Cell Lung Cancer
EGFR wild-type + MET amplification
Non Small Cell Lung Cancer
tepotinib
Sensitive: C3 – Early Trials
tepotinib
Sensitive
:
C3
tepotinib
Sensitive: C3 – Early Trials
tepotinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib + tepotinib
Sensitive: C3 – Early Trials
osimertinib + tepotinib
Sensitive
:
C3
osimertinib + tepotinib
Sensitive: C3 – Early Trials
osimertinib + tepotinib
Sensitive
:
C3
EGFR mutation + MET-CEP7 fusion
Non Small Cell Lung Cancer
EGFR mutation + MET-CEP7 fusion
Non Small Cell Lung Cancer
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
tepotinib + capmatinib
Sensitive: C3 – Early Trials
tepotinib + capmatinib
Sensitive
:
C3
tepotinib + capmatinib
Sensitive: C3 – Early Trials
tepotinib + capmatinib
Sensitive
:
C3
MET amplification + RB1 wild-type
Non Small Cell Lung Cancer
MET amplification + RB1 wild-type
Non Small Cell Lung Cancer
tepotinib
Sensitive: C3 – Early Trials
tepotinib
Sensitive
:
C3
tepotinib
Sensitive: C3 – Early Trials
tepotinib
Sensitive
:
C3
HLA-DRB1-MET fusion
Non Small Cell Lung Cancer
HLA-DRB1-MET fusion
Non Small Cell Lung Cancer
tepotinib
Sensitive: C4 – Case Studies
tepotinib
Sensitive
:
C4
tepotinib
Sensitive: C4 – Case Studies
tepotinib
Sensitive
:
C4
MET exon 14 mutation + MET amplification + PD-L1 overexpression
Lung Adenocarcinoma
MET exon 14 mutation + MET amplification + PD-L1 overexpression
Lung Adenocarcinoma
tepotinib
Sensitive: C4 – Case Studies
tepotinib
Sensitive
:
C4
tepotinib
Sensitive: C4 – Case Studies
tepotinib
Sensitive
:
C4
PD-L1 overexpression + MET exon 14 mutation
Non Small Cell Lung Cancer
PD-L1 overexpression + MET exon 14 mutation
Non Small Cell Lung Cancer
tepotinib
Sensitive: C4 – Case Studies
tepotinib
Sensitive
:
C4
tepotinib
Sensitive: C4 – Case Studies
tepotinib
Sensitive
:
C4
MET overexpression + MUC5B overexpression
Gastric Cancer
MET overexpression + MUC5B overexpression
Gastric Cancer
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
MET overexpression
Gastric Cancer
MET overexpression
Gastric Cancer
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
MET positive
Gastric Cancer
MET positive
Gastric Cancer
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
KRAS G12C
Non Small Cell Lung Cancer
KRAS G12C
Non Small Cell Lung Cancer
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
KRAS mutation
Non Small Cell Lung Cancer
KRAS mutation
Non Small Cell Lung Cancer
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
tepotinib
Sensitive: D – Preclinical
tepotinib
Sensitive
:
D
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