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BIOMARKER:
EGFR exon 19 deletion
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR mutation (196)
EGFR L858R (90)
EGFR T790M (64)
EGFR exon 20 insertion (50)
EGFR wild-type (41)
EGFR L861Q (23)
EGFR C797S (22)
EGFR exon 21 mutation (20)
EGFR L858R + EGFR T790M (16)
EGFR exon 19 mutation (14)
EGFR A763_Y764insFQEA (13)
EGFR G719X (13)
EGFR S768I (12)
EGFR mutation + TP53 mutation (11)
EGFR C797S + EGFR T790M + EGFR L858R (9)
EGFR C797S + EGFR T790M + EGFR exon 19 deletion (9)
EGFR E746_A750del (8)
EGFR exon 20 mutation (8)
EGFRvIII mutation (8)
EGFR G719A (7)
EGFR G719S (7)
EGFR L747P (7)
EGFR exon 18 mutation (7)
EGFR T790M + EGFR C797S (6)
EGFR exon 19 deletion + EGFR L861Q (6)
EGFR mutation + BRAF V600E (6)
EGFR wild-type + ALK wild-type (6)
EGFR G719X + EGFR S768I (5)
EGFR K745_E746insIPVAIK (5)
EGFR G719C (4)
EGFR L861Q + EGFR G719X (4)
EGFR S492R (4)
EGFR mutation + KRAS mutation (4)
EGFR mutation + PIK3CA mutation (4)
EGFR D770 delinsGY (3)
EGFR D770_N771insSVD (3)
EGFR E709K (3)
EGFR E709_T710delinsD (3)
EGFR E746_S752delinsV (3)
EGFR G724S (3)
EGFR H773_V774insH (3)
EGFR L718Q (3)
EGFR L833V + EGFR H835L (3)
EGFR L858R + EGFR M766Q (3)
EGFR R521K (3)
EGFR T790M negative (3)
EGFR T854A (3)
EGFR exon 18-25 duplication (3)
EGFR exon 19 deletion + EGFR C797S (3)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S (3)
EGFR mutation + CREBBP mutation (3)
HER-2 V777L + EGFR L858R (3)
EGFR A767_V769dup (2)
EGFR D761Y (2)
EGFR D770_N771insGT (2)
EGFR E114K (2)
EGFR G465R (2)
EGFR G63R (2)
EGFR G719A + EGFR G779C (2)
EGFR G719C + EGFR S768I (2)
EGFR G719S + EGFR L861Q (2)
EGFR G874S (2)
EGFR H1975 (2)
EGFR K708R (2)
EGFR L747-S752 del (2)
EGFR L747_A750delinsP (2)
EGFR L833F + EGFR L861Q (2)
EGFR L858R + EGFR A871G (2)
EGFR L858R + EGFR L718Q (2)
EGFR L858R + RBM10 Y36* (2)
EGFR L858R + TP53 mutation (2)
EGFR L860R (2)
EGFR L861R (2)
EGFR N771delinsKG (2)
EGFR P596L (2)
EGFR R165Q (2)
EGFR R222C (2)
EGFR S645C + EGFR L858R (2)
EGFR T790M + KRAS mutation (2)
EGFR T790M + PIK3CA H1047R (2)
EGFR V802I + KRAS mutation (2)
EGFR exon 19 duplication (2)
EGFR exon 19 insertion (2)
EGFR exon 20 insertion + EGFR T790M (2)
EGFR mutation + ATM mutation (2)
EGFR mutation + BRAF V600 (2)
EGFR mutation + CDKN2A mutation (2)
EGFR mutation + EGFR T790M (2)
EGFR mutation + MET mutation (2)
EGFR mutation + NRAS Q61K (2)
EGFR mutation + PTEN mutation (2)
EGFR mutation + TP53 mutation + ARID1A mutation (2)
EGFR mutation + TP53 mutation + BRCA1 mutation (2)
EGFR mutation + TP53 mutation + NF1 mutation (2)
EGFR mutation + TP53 mutation + PTEN mutation (2)
EGFR mutation + TP53 mutation + RB1 mutation (2)
EGFR T790L (2)
EGFR delE709_T710insD (2)
KRAS mutation + EGFR wild-type (2)
MET exon 14 mutation + EGFR exon 20 insertion (2)
ALK L1152R + EGFR mutation (1)
ALK rearrangement + ALK T1151M + ALK L1198F + EGFR A839V (1)
ALK rearrangement + EGFR D761N + KRAS V14I (1)
ALK rearrangement + TP53 R175H + EGFR A839V + PI3KCA mutation (1)
BRAF mutation + EGFR mutation (1)
CDK4 mutation + EGFR mutation (1)
DDR + EGFR mutation (1)
EGFR 181946 C>T (1)
EGFR A289V (1)
EGFR A750P (1)
EGFR A763V (1)
EGFR A767_V769dupASV (1)
EGFR A767dupASV (1)
EGFR A859T (1)
EGFR C796S (1)
EGFR C796S + EGFR V802I (1)
EGFR C797S + EGFR C796S (1)
EGFR C797S + EGFR exon 20 insertion (1)
EGFR D770_N771insGL (1)
EGFR D770_N771insGT + EGFR V774_C775insHV (1)
EGFR E690K (1)
EGFR E709A + EGFR G719C (1)
EGFR E709G (1)
EGFR E709Q (1)
EGFR E746 (1)
EGFR E746G (1)
EGFR E746_T751delinsl (1)
EGFR E758D (1)
EGFR E884K (1)
EGFR G2607A (1)
EGFR G709T (1)
EGFR G719A + EGFR I706T (1)
EGFR G719A + EGFR L833V (1)
EGFR G719A + EGFR R776C (1)
EGFR G719A + EGFR S768I (1)
EGFR G719A + EGFR T790M (1)
EGFR G719C + EGFR E709V (1)
EGFR G719D (1)
EGFR G719S + EGFR S768I (1)
EGFR G719X + EGFR E709F (1)
EGFR G719X + EGFR L861Q + EGFR S768I (1)
EGFR G719X + TP53 mutation (1)
EGFR G724S + EGFR R776H (1)
EGFR G735R (1)
EGFR G796S (1)
EGFR G836S (1)
EGFR H773L + EGFR V774M (1)
EGFR H773_V774insNPH (1)
EGFR H773delinsNPY (1)
EGFR H773delinsYNPY (1)
EGFR H835L (1)
EGFR I744_K745insKIPVAI (1)
EGFR K467T (1)
EGFR K757R (1)
EGFR L718V + TP53 V727M + EGFR L858R (1)
EGFR L746_T70delinsS (1)
EGFR L746_T750del (1)
EGFR L747S (1)
EGFR L747_A750>P (1)
EGFR L747_P753delinsS (1)
EGFR L747_T751delinsP (1)
EGFR L747_T751delinsS (1)
EGFR L747_T753delinsS (1)
EGFR L833V (1)
EGFR L8585R + EGFR T790M + RBM10 G840fs*7 (1)
EGFR L858R + ALK R1275Q (1)
EGFR L858R + ALK rearrangement (1)
EGFR L858R + EGFR C797S (1)
EGFR L858R + EGFR D761Y (1)
EGFR L858R + EGFR E709G (1)
EGFR L858R + EGFR E709X (1)
EGFR L858R + EGFR E709X + CTNNB1 mutation (1)
EGFR L858R + EGFR E884K (1)
EGFR L858R + EGFR L747V (1)
EGFR L858R + EGFR R776H (1)
EGFR L858R + EGFR S765I (1)
EGFR L858R + EGFR S768I (1)
EGFR L858R + EGFR T854A (1)
EGFR L858R + EGFR V843I (1)
EGFR L858R + EGFR exon 21 deletion (1)
EGFR L858R + FGF3 mutation (1)
EGFR L858R + IDH1 R132C (1)
EGFR L858R + PIK3CA H1047R + PIK3CA E545K (1)
EGFR L858R + RBM10 2167-1 G>T (1)
EGFR L858R + RBM10 Q255* (1)
EGFR L858R + RBM10 Q595* (1)
EGFR L858R + TP53 R273C + HER-2 S442L (1)
EGFR L858R + TP53 wild-type (1)
EGFR L861P (1)
EGFR L861Q + EGFR exon 20 insertion (1)
EGFR L861Q + TP53 mutation (1)
EGFR L861Q + TP53 mutation + RB1 mutation (1)
EGFR L861X (1)
EGFR M277E (1)
EGFR M766Q (1)
EGFR M766_A767insASV (1)
EGFR N771_P772insH (1)
EGFR N771_P772insVal (1)
EGFR P546S (1)
EGFR P753S (1)
EGFR P772_H773insYNP (1)
EGFR P772_H773insYNP + EGFR H773Y (1)
EGFR P772_V774insPHV (1)
EGFR Q787Q (1)
EGFR R1052K (1)
EGFR R451C (1)
EGFR R776C + EGFR L861Q (1)
EGFR R776H (1)
EGFR R776H + EGFR C797S (1)
EGFR R776H + EGFR L861Q (1)
EGFR S464L (1)
EGFR S720I (1)
EGFR S752_I759del (1)
EGFR S768I + TP53 mutation (1)
EGFR S768_D770dup (1)
EGFR S768_D770dupSVD (1)
EGFR S768dupSVD (1)
EGFR S784F (1)
EGFR T263P (1)
EGFR T751_I759>S (1)
EGFR T790I (1)
EGFR T790M + BRAF V600E (1)
EGFR T790M + EGFR L792F (1)
EGFR T790M + EGFR L833V + EGFR H835L (1)
EGFR T790M + EGFR L861Q (1)
EGFR T790M + EGFR S768I + EGFR L858R (1)
EGFR T790M + HER-2 mutation (1)
EGFR T790M + KRAS G12V (1)
EGFR T790M + MET mutation (1)
EGFR T790M + PARP1 mutation (1)
EGFR T790M + PIK3CA Mutation (1)
EGFR T790M + TP53 R237C (1)
EGFR T854A + EGFR T790M (1)
EGFR T858R (1)
EGFR V769A (1)
EGFR V769_770insASV (1)
EGFR V774_C775insHV (1)
EGFR V786M (1)
EGFR V802I (1)
EGFR V834L (1)
EGFR Y764_V765insHH (1)
EGFR exon 18 mutation + EGFR exon 21 mutation (1)
EGFR exon 19 deletion + ALK mutation (1)
EGFR exon 19 deletion + ATM S1455fs*36 + MYC E62K (1)
EGFR exon 19 deletion + BRAF V600E (1)
EGFR exon 19 deletion + BRCA2 mutation (1)
EGFR exon 19 deletion + EGFR G724S + EGFR T790M (1)
EGFR exon 19 deletion + EGFR T790L (1)
EGFR exon 19 deletion + TP53 exon 8 mutation (1)
EGFR exon 19 deletion + TP53 mutation (1)
EGFR exon 19 mutation + EGFR C797S + PIK3CA mutation (1)
EGFR exon 20 insertion + EGFR G719X + EGFR L858R (1)
EGFR exon 20 insertion + NRAS G13V + NF1 R69fs + NF1 S340fs (1)
EGFR exon 20 insertion + TP53 G244A + SPTA1 mutation (1)
EGFR exon 20 mutation + EGFR V774M + EGFR S768I (1)
EGFR exon 21 deletion + EGFR L858R + MET Exon 14 mutation (1)
EGFR exon 21 mutation + EGFR L858R (1)
EGFR mutation + ALK mutation (1)
EGFR mutation + BRAF G469A (1)
EGFR mutation + BRAF mutation + TP53 mutation (1)
EGFR mutation + CTBP2 rs376695472 (1)
EGFR mutation + CTBP2 rs945665113 (1)
EGFR mutation + EGFR T790M + EGFR C797S (1)
EGFR mutation + FAT3 mutation (1)
EGFR mutation + GRM8 mutation (1)
EGFR mutation + HLA-DRB5 rs1071748 (1)
EGFR mutation + HLA-DRB5 rs184278615 (1)
EGFR mutation + HLA-DRB5 rs20146916 (1)
EGFR mutation + IDH1 mutation (1)
EGFR mutation + KIR3DL1 rs199822561 (1)
EGFR mutation + KIR3DL1 rs200821495 (1)
EGFR mutation + KIR3DL1 rs72629105 (1)
EGFR mutation + KIR3DL2 rs973541788 (1)
EGFR mutation + LRP1B mutation (1)
EGFR mutation + MDM4 *32C>A (1)
EGFR mutation + MET Y1003N (1)
EGFR mutation + NOTCH1 mutation (1)
EGFR mutation + RB1 mutation (1)
EGFR mutation + SMAD4 mutation (1)
EGFR mutation + TP53 exon 6 mutation (1)
EGFR mutation + TP53 exon 7 mutation (1)
EGFR mutation + UBXN11 mutation (1)
EGFR mutation + ZNF217 mutation (1)
EGFR mutation+ IDH1 R132H (1)
EGFR rearrangement (1)
EGFR wild-type + ALK wild-type + ROS1 wild-type (1)
EGFR wild-type + ALK wild-type + STK11 mutation (1)
EGFR wild-type + MET wild-type (1)
EGFR-SEPTIN14 rearrangement (1)
EGFR G729A + EGFR L858R (1)
EGFR T790M + TP53 mutation (1)
IDH1 R132C + EGFR L861Q (1)
IDH2 R140W + EGFR L858R (1)
KRAS codon 12 mutation + KRAS codon 13 mutation + EGFR mutation (1)
MTOR L1433S + EGFR L858R + EGFR T790M (1)
EGFR A839V (0)
EGFR E709A (0)
EGFR E709F (0)
EGFR G779C (0)
EGFR G873E (0)
EGFR H773L (0)
EGFR K754E (0)
EGFR L747_S752del (0)
EGFR L747_T750del (0)
EGFR L858R + EGFR G779S (0)
EGFR L858R + RBM10 Q255 (0)
EGFR R776C (0)
EGFR S765I (0)
EGFR T785A + EGFR L861Q + EGFR H297_E298 (0)
EGFR V774M (0)
EGFR mutation + APC mutation (0)
EGFR rs4947492 (0)
MET exon 14 skipping mutation + EGFR G709T (0)
EGFR mutation (196)
EGFR L858R (90)
EGFR T790M (64)
EGFR exon 20 insertion (50)
EGFR wild-type (41)
EGFR L861Q (23)
EGFR C797S (22)
EGFR exon 21 mutation (20)
EGFR L858R + EGFR T790M (16)
EGFR exon 19 mutation (14)
EGFR A763_Y764insFQEA (13)
EGFR G719X (13)
EGFR S768I (12)
EGFR mutation + TP53 mutation (11)
EGFR C797S + EGFR T790M + EGFR L858R (9)
EGFR C797S + EGFR T790M + EGFR exon 19 deletion (9)
EGFR E746_A750del (8)
EGFR exon 20 mutation (8)
EGFRvIII mutation (8)
EGFR G719A (7)
EGFR G719S (7)
EGFR L747P (7)
EGFR exon 18 mutation (7)
EGFR T790M + EGFR C797S (6)
EGFR exon 19 deletion + EGFR L861Q (6)
EGFR mutation + BRAF V600E (6)
EGFR wild-type + ALK wild-type (6)
EGFR G719X + EGFR S768I (5)
EGFR K745_E746insIPVAIK (5)
EGFR G719C (4)
EGFR L861Q + EGFR G719X (4)
EGFR S492R (4)
EGFR mutation + KRAS mutation (4)
EGFR mutation + PIK3CA mutation (4)
EGFR D770 delinsGY (3)
EGFR D770_N771insSVD (3)
EGFR E709K (3)
EGFR E709_T710delinsD (3)
EGFR E746_S752delinsV (3)
EGFR G724S (3)
EGFR H773_V774insH (3)
EGFR L718Q (3)
EGFR L833V + EGFR H835L (3)
EGFR L858R + EGFR M766Q (3)
EGFR R521K (3)
EGFR T790M negative (3)
EGFR T854A (3)
EGFR exon 18-25 duplication (3)
EGFR exon 19 deletion + EGFR C797S (3)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S (3)
EGFR mutation + CREBBP mutation (3)
HER-2 V777L + EGFR L858R (3)
EGFR A767_V769dup (2)
EGFR D761Y (2)
EGFR D770_N771insGT (2)
EGFR E114K (2)
EGFR G465R (2)
EGFR G63R (2)
EGFR G719A + EGFR G779C (2)
EGFR G719C + EGFR S768I (2)
EGFR G719S + EGFR L861Q (2)
EGFR G874S (2)
EGFR H1975 (2)
EGFR K708R (2)
EGFR L747-S752 del (2)
EGFR L747_A750delinsP (2)
EGFR L833F + EGFR L861Q (2)
EGFR L858R + EGFR A871G (2)
EGFR L858R + EGFR L718Q (2)
EGFR L858R + RBM10 Y36* (2)
EGFR L858R + TP53 mutation (2)
EGFR L860R (2)
EGFR L861R (2)
EGFR N771delinsKG (2)
EGFR P596L (2)
EGFR R165Q (2)
EGFR R222C (2)
EGFR S645C + EGFR L858R (2)
EGFR T790M + KRAS mutation (2)
EGFR T790M + PIK3CA H1047R (2)
EGFR V802I + KRAS mutation (2)
EGFR exon 19 duplication (2)
EGFR exon 19 insertion (2)
EGFR exon 20 insertion + EGFR T790M (2)
EGFR mutation + ATM mutation (2)
EGFR mutation + BRAF V600 (2)
EGFR mutation + CDKN2A mutation (2)
EGFR mutation + EGFR T790M (2)
EGFR mutation + MET mutation (2)
EGFR mutation + NRAS Q61K (2)
EGFR mutation + PTEN mutation (2)
EGFR mutation + TP53 mutation + ARID1A mutation (2)
EGFR mutation + TP53 mutation + BRCA1 mutation (2)
EGFR mutation + TP53 mutation + NF1 mutation (2)
EGFR mutation + TP53 mutation + PTEN mutation (2)
EGFR mutation + TP53 mutation + RB1 mutation (2)
EGFR T790L (2)
EGFR delE709_T710insD (2)
KRAS mutation + EGFR wild-type (2)
MET exon 14 mutation + EGFR exon 20 insertion (2)
ALK L1152R + EGFR mutation (1)
ALK rearrangement + ALK T1151M + ALK L1198F + EGFR A839V (1)
ALK rearrangement + EGFR D761N + KRAS V14I (1)
ALK rearrangement + TP53 R175H + EGFR A839V + PI3KCA mutation (1)
BRAF mutation + EGFR mutation (1)
CDK4 mutation + EGFR mutation (1)
DDR + EGFR mutation (1)
EGFR 181946 C>T (1)
EGFR A289V (1)
EGFR A750P (1)
EGFR A763V (1)
EGFR A767_V769dupASV (1)
EGFR A767dupASV (1)
EGFR A859T (1)
EGFR C796S (1)
EGFR C796S + EGFR V802I (1)
EGFR C797S + EGFR C796S (1)
EGFR C797S + EGFR exon 20 insertion (1)
EGFR D770_N771insGL (1)
EGFR D770_N771insGT + EGFR V774_C775insHV (1)
EGFR E690K (1)
EGFR E709A + EGFR G719C (1)
EGFR E709G (1)
EGFR E709Q (1)
EGFR E746 (1)
EGFR E746G (1)
EGFR E746_T751delinsl (1)
EGFR E758D (1)
EGFR E884K (1)
EGFR G2607A (1)
EGFR G709T (1)
EGFR G719A + EGFR I706T (1)
EGFR G719A + EGFR L833V (1)
EGFR G719A + EGFR R776C (1)
EGFR G719A + EGFR S768I (1)
EGFR G719A + EGFR T790M (1)
EGFR G719C + EGFR E709V (1)
EGFR G719D (1)
EGFR G719S + EGFR S768I (1)
EGFR G719X + EGFR E709F (1)
EGFR G719X + EGFR L861Q + EGFR S768I (1)
EGFR G719X + TP53 mutation (1)
EGFR G724S + EGFR R776H (1)
EGFR G735R (1)
EGFR G796S (1)
EGFR G836S (1)
EGFR H773L + EGFR V774M (1)
EGFR H773_V774insNPH (1)
EGFR H773delinsNPY (1)
EGFR H773delinsYNPY (1)
EGFR H835L (1)
EGFR I744_K745insKIPVAI (1)
EGFR K467T (1)
EGFR K757R (1)
EGFR L718V + TP53 V727M + EGFR L858R (1)
EGFR L746_T70delinsS (1)
EGFR L746_T750del (1)
EGFR L747S (1)
EGFR L747_A750>P (1)
EGFR L747_P753delinsS (1)
EGFR L747_T751delinsP (1)
EGFR L747_T751delinsS (1)
EGFR L747_T753delinsS (1)
EGFR L833V (1)
EGFR L8585R + EGFR T790M + RBM10 G840fs*7 (1)
EGFR L858R + ALK R1275Q (1)
EGFR L858R + ALK rearrangement (1)
EGFR L858R + EGFR C797S (1)
EGFR L858R + EGFR D761Y (1)
EGFR L858R + EGFR E709G (1)
EGFR L858R + EGFR E709X (1)
EGFR L858R + EGFR E709X + CTNNB1 mutation (1)
EGFR L858R + EGFR E884K (1)
EGFR L858R + EGFR L747V (1)
EGFR L858R + EGFR R776H (1)
EGFR L858R + EGFR S765I (1)
EGFR L858R + EGFR S768I (1)
EGFR L858R + EGFR T854A (1)
EGFR L858R + EGFR V843I (1)
EGFR L858R + EGFR exon 21 deletion (1)
EGFR L858R + FGF3 mutation (1)
EGFR L858R + IDH1 R132C (1)
EGFR L858R + PIK3CA H1047R + PIK3CA E545K (1)
EGFR L858R + RBM10 2167-1 G>T (1)
EGFR L858R + RBM10 Q255* (1)
EGFR L858R + RBM10 Q595* (1)
EGFR L858R + TP53 R273C + HER-2 S442L (1)
EGFR L858R + TP53 wild-type (1)
EGFR L861P (1)
EGFR L861Q + EGFR exon 20 insertion (1)
EGFR L861Q + TP53 mutation (1)
EGFR L861Q + TP53 mutation + RB1 mutation (1)
EGFR L861X (1)
EGFR M277E (1)
EGFR M766Q (1)
EGFR M766_A767insASV (1)
EGFR N771_P772insH (1)
EGFR N771_P772insVal (1)
EGFR P546S (1)
EGFR P753S (1)
EGFR P772_H773insYNP (1)
EGFR P772_H773insYNP + EGFR H773Y (1)
EGFR P772_V774insPHV (1)
EGFR Q787Q (1)
EGFR R1052K (1)
EGFR R451C (1)
EGFR R776C + EGFR L861Q (1)
EGFR R776H (1)
EGFR R776H + EGFR C797S (1)
EGFR R776H + EGFR L861Q (1)
EGFR S464L (1)
EGFR S720I (1)
EGFR S752_I759del (1)
EGFR S768I + TP53 mutation (1)
EGFR S768_D770dup (1)
EGFR S768_D770dupSVD (1)
EGFR S768dupSVD (1)
EGFR S784F (1)
EGFR T263P (1)
EGFR T751_I759>S (1)
EGFR T790I (1)
EGFR T790M + BRAF V600E (1)
EGFR T790M + EGFR L792F (1)
EGFR T790M + EGFR L833V + EGFR H835L (1)
EGFR T790M + EGFR L861Q (1)
EGFR T790M + EGFR S768I + EGFR L858R (1)
EGFR T790M + HER-2 mutation (1)
EGFR T790M + KRAS G12V (1)
EGFR T790M + MET mutation (1)
EGFR T790M + PARP1 mutation (1)
EGFR T790M + PIK3CA Mutation (1)
EGFR T790M + TP53 R237C (1)
EGFR T854A + EGFR T790M (1)
EGFR T858R (1)
EGFR V769A (1)
EGFR V769_770insASV (1)
EGFR V774_C775insHV (1)
EGFR V786M (1)
EGFR V802I (1)
EGFR V834L (1)
EGFR Y764_V765insHH (1)
EGFR exon 18 mutation + EGFR exon 21 mutation (1)
EGFR exon 19 deletion + ALK mutation (1)
EGFR exon 19 deletion + ATM S1455fs*36 + MYC E62K (1)
EGFR exon 19 deletion + BRAF V600E (1)
EGFR exon 19 deletion + BRCA2 mutation (1)
EGFR exon 19 deletion + EGFR G724S + EGFR T790M (1)
EGFR exon 19 deletion + EGFR T790L (1)
EGFR exon 19 deletion + TP53 exon 8 mutation (1)
EGFR exon 19 deletion + TP53 mutation (1)
EGFR exon 19 mutation + EGFR C797S + PIK3CA mutation (1)
EGFR exon 20 insertion + EGFR G719X + EGFR L858R (1)
EGFR exon 20 insertion + NRAS G13V + NF1 R69fs + NF1 S340fs (1)
EGFR exon 20 insertion + TP53 G244A + SPTA1 mutation (1)
EGFR exon 20 mutation + EGFR V774M + EGFR S768I (1)
EGFR exon 21 deletion + EGFR L858R + MET Exon 14 mutation (1)
EGFR exon 21 mutation + EGFR L858R (1)
EGFR mutation + ALK mutation (1)
EGFR mutation + BRAF G469A (1)
EGFR mutation + BRAF mutation + TP53 mutation (1)
EGFR mutation + CTBP2 rs376695472 (1)
EGFR mutation + CTBP2 rs945665113 (1)
EGFR mutation + EGFR T790M + EGFR C797S (1)
EGFR mutation + FAT3 mutation (1)
EGFR mutation + GRM8 mutation (1)
EGFR mutation + HLA-DRB5 rs1071748 (1)
EGFR mutation + HLA-DRB5 rs184278615 (1)
EGFR mutation + HLA-DRB5 rs20146916 (1)
EGFR mutation + IDH1 mutation (1)
EGFR mutation + KIR3DL1 rs199822561 (1)
EGFR mutation + KIR3DL1 rs200821495 (1)
EGFR mutation + KIR3DL1 rs72629105 (1)
EGFR mutation + KIR3DL2 rs973541788 (1)
EGFR mutation + LRP1B mutation (1)
EGFR mutation + MDM4 *32C>A (1)
EGFR mutation + MET Y1003N (1)
EGFR mutation + NOTCH1 mutation (1)
EGFR mutation + RB1 mutation (1)
EGFR mutation + SMAD4 mutation (1)
EGFR mutation + TP53 exon 6 mutation (1)
EGFR mutation + TP53 exon 7 mutation (1)
EGFR mutation + UBXN11 mutation (1)
EGFR mutation + ZNF217 mutation (1)
EGFR mutation+ IDH1 R132H (1)
EGFR rearrangement (1)
EGFR wild-type + ALK wild-type + ROS1 wild-type (1)
EGFR wild-type + ALK wild-type + STK11 mutation (1)
EGFR wild-type + MET wild-type (1)
EGFR-SEPTIN14 rearrangement (1)
EGFR G729A + EGFR L858R (1)
EGFR T790M + TP53 mutation (1)
IDH1 R132C + EGFR L861Q (1)
IDH2 R140W + EGFR L858R (1)
KRAS codon 12 mutation + KRAS codon 13 mutation + EGFR mutation (1)
MTOR L1433S + EGFR L858R + EGFR T790M (1)
EGFR A839V (0)
EGFR E709A (0)
EGFR E709F (0)
EGFR G779C (0)
EGFR G873E (0)
EGFR H773L (0)
EGFR K754E (0)
EGFR L747_S752del (0)
EGFR L747_T750del (0)
EGFR L858R + EGFR G779S (0)
EGFR L858R + RBM10 Q255 (0)
EGFR R776C (0)
EGFR S765I (0)
EGFR T785A + EGFR L861Q + EGFR H297_E298 (0)
EGFR V774M (0)
EGFR mutation + APC mutation (0)
EGFR rs4947492 (0)
MET exon 14 skipping mutation + EGFR G709T (0)
›
Related tests:
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (20)
cobas® EGFR Mutation Test v2 (13)
Oncomine™ Dx Target Test (10)
therascreen® EGFR RGQ PCR Kit (5)
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (20)
cobas® EGFR Mutation Test v2 (13)
Oncomine™ Dx Target Test (10)
therascreen® EGFR RGQ PCR Kit (5)
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
Associations
(79)
News
Trials
Search handles
@ADesaiMD
@APassaroMD
@AndresFCardonaZ
@DrChoueiri
@DrSteveMartin
@PatelOncology
@StephenVLiu
@Tony_Calles
@VivekSubbiah
@christine_lovly
@drgandara
@esinghimd
@mlazqui
@wangyub
Search handles
@ADesaiMD
@APassaroMD
@AndresFCardonaZ
@DrChoueiri
@DrSteveMartin
@PatelOncology
@StephenVLiu
@Tony_Calles
@VivekSubbiah
@christine_lovly
@drgandara
@esinghimd
@mlazqui
@wangyub
Filter by
Latest
10ms
ASCO 2023 Plenary abstract LBA3 Dr Roy Herbst lead author of the ADAURA study in EGFRm (ex19del/L858R) stage IB, II or IIIA NSCLC; overall survival benefit of 51% reduction in risk of death in the overall population. #ASCO2023 #precisiononcology #PoetOncology #targetedtreatment (@POETOncology)
10 months ago
Clinical • Late-breaking abstract
|
EGFR L858R • EGFR exon 19 deletion
10ms
Dear professor,i sent you a DM for my mom.She has NSCLCadeno with bone mets a rare EGFR exon19 del E756T751 can you please check (@merttopraakkk)
10 months ago
EGFR (Epidermal growth factor receptor)
|
EGFR exon 19 deletion
11ms
3/ 📌 On Dec 18, 2020, the @FDAOncology gave a thumbs up 👍 to osimertinib for adjuvant therapy post tumor resection in NSCLC patients with EGFR exon 19 deletions or exon 21 L858R mutations. ADAURA study showed ➡️ Median DFS not reached vs 19.6 months on placebo (HR 0.17,… https://t.co/zLg1uyLDCc (@ADesaiMD)
11 months ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR L858R • EGFR exon 19 deletion
|
Tagrisso (osimertinib)
12ms
NSCLC with an #EGFR exon 20 insertion mutation is different from exon 19 deletion and exon 21 L858R! Drs. Byoung-Chul Cho and @charocampelo describe their approach and Marcia Horn @Exon20Group provides perspective in this episode of #LungCancerConsidered https://t.co/i16OujxoC7 (@StephenVLiu)
12 months ago
EGFR exon 20
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR L858R • EGFR exon 19 deletion • EGFR exon 20 insertion • EGFR exon 20 mutation • EGFR L858R + EGFR exon 19 deletion
1year
Real-world cohort analysis of EGFR+ lung cancer transformed into SCLC reveals APOBEC mutations & seen more commonly in EGFR exon19del variants. Histologic transformation now documented in several oncogene-addicted lung cancers. @christine_lovly @VanderbiltU #SCLC23 @EGFRResisters (@LUNGevity)
1 year ago
Clinical • Real-world evidence • Real-world
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR exon 19 deletion
1year
🆕in @CCR_AACR an analysis investigating the efficacy of Osi in pts with lung cancer harbouring *uncommon* EGFR exon 19 del mut’s E746_A750del was associated with significantly prolonged mPFS with 1L Osi vs. L747_A750>P (21.3 vs. 11.7m; [HR] 0.52 ; p=0.043). Understanding… https://t.co/LkXdWa0p8E (@APassaroMD)
1 year ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR exon 19 deletion • EGFR E746
1year
Efficacy of osimertinib in patients with lung cancer positive for uncommon EGFR exon 19 deletion mutations https://t.co/1PQ124GUBu (@AndresFCardonaZ)
1 year ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR exon 19 deletion
|
Tagrisso (osimertinib)
1year
2/ @LeXiuning @MDAndersonNews on EGFR mutations: ▪️EGFR mutations ~10-20% NSCLC pts in Europe/N America, & up to 50% of patients in Asia ▪️Exon 19 del & exon 21 L858R most common (~85-90%) ▪️🔑 Most frequent uncommon mutations to know: G719X, S768I, L861Q, & exon 20 insertions (@esinghimd)
1 year ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR L858R • EGFR exon 19 deletion • EGFR L861Q • EGFR G719X • EGFR S768I
1year
🦄 Osimertinib in non-exon 19 deletion or L858R EGFR mutations (excluded from FLAURA trial) Important issue, as they represent ≈ 20% of EGFR mutations in the clinic. Thrilled to participate in this study now @IASLC 🔝 as Editor’s choice @JTOonline #LCSM https://t.co/adB3FJKezV (@Tony_Calles)
1 year ago
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR L858R • EGFR exon 19 deletion
|
Tagrisso (osimertinib)
over1year
Hey #lcsm precision onc guru friends- you want to be an Alkemist and help w challenging case? Young pt w egfr ex19 del, nice response to osi for yr+, now progression incl CNS CNS specimen now shows STRN-ALK fusion along w ex19del. Getting SRS to resid CNS dx What is best syst tx? (@DrSteveMartin)
over 1 year ago
EGFR (Epidermal growth factor receptor) • STRN (Striatin)
|
EGFR exon 19 deletion • ALK fusion • STRN-ALK fusion
over1year
My fellow #3MusketeersforLCSM presents a very interesting case on “Concomitant EGFR exon 19 deletion and ERBB2 mutation in a patient with metastatic non-small cell lung cancer” #EGFRSummit22 #lcsm @EGFRSummit @EGFRResisters (@esinghimd)
over 1 year ago
Clinical
|
EGFR (Epidermal growth factor receptor) • HER-2 (Human epidermal growth factor receptor 2)
|
EGFR mutation • HER-2 mutation • EGFR exon 19 deletion
over1year
Real-world data with afatinib in Spanish patients with treatment-naïve non-small-cell lung cancer harboring exon 19 deletions in epidermal growth factor receptor (Del19 EGFR): Clinical experience of the Galician Lung Cancer Group https://t.co/feIIxBSq30 (@mlazqui)
over 1 year ago
Clinical • Real-world evidence
|
EGFR (Epidermal growth factor receptor)
|
EGFR exon 19 deletion
|
Gilotrif (afatinib)
over1year
Nice talk on EGFR (it’s not enough to just name the street anymore, you have to say the whole address- exon 19 del, exon 20 insertion, L858R etc) in mNSCLC by @MdCurioni @LungSummit (@PatelOncology)
over 1 year ago
EGFR (Epidermal growth factor receptor)
|
EGFR L858R • EGFR exon 19 deletion
over1year
Using computational & experimental models in a study funded by our division, @MeilerLab, @christine_lovly, et al. revealed allele-specific activation, enzyme kinetics, & inhibitor sensitivities of EGFR exon 19 deletion mutations in #lungcancer @PNASNews https://t.co/Q2BVXBA8r6. (@NCICancerBio)
over 1 year ago
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR exon 19 deletion
over1year
During a live virtual event, Benjamin P. Levy, MD, discussed the case of a patient with non–small cell lung cancer and an EGFR exon 19 deletion. This is the second of two articles based on this event. #NSCLC #lcsm | @benlevylungdoc @KimmelCancerCtr https://t.co/VfOEuk5tv8 (@TargetedOnc)
over 1 year ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR exon 19 deletion
almost2years
🧵11 We analyze a large cohort (n=121) of putative tSCLC w/ driver mut typically found in NSCLC ➡️EGFR (ex19del > L858R in SCLC cases!) ➡️ALK ➡️ROS1 ➡️RET ➡️NTRK Need for rebiopsy of all driver+ NSCLC to look for SCLC @EGFRResisters @ALKLungCancer @ros1cancer @RetRenegades (@christine_lovly)
almost 2 years ago
Clinical
|
EGFR (Epidermal growth factor receptor) • ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS) • NTRK (Neurotrophic receptor tyrosine kinase)
|
EGFR L858R • EGFR exon 19 deletion
almost2years
I'm very excited to share our recent PNAS paper with the Lovly and Meiler groups!! @christine_lovly @MeilerLab Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer. https://t.co/oLL0mj37Ha (@awsmith)
almost 2 years ago
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR exon 19 deletion
almost2years
67, f, right upper lobe lobectomy, pT2aN1M0 adenocarcinoma harboring an EGFR exon 19 deletion and PDL1 10%. next step? 1. cis/pem x4; 2 cis/pemx4 erlotinibx2y 3. cis/pemetrexedx4 Osix 2 y 4. cis/ pemx4 durvalumab x1y. From ASCO SEP DIGITAL qBANK #lungcancer (@wangyub)
almost 2 years ago
EGFR (Epidermal growth factor receptor) • PD-L1 (Programmed death ligand 1)
|
EGFR exon 19 deletion
|
erlotinib • Imfinzi (durvalumab) • pemetrexed
almost2years
AENEAS: Randomized 1L Phase III Trial of Aumolertinib Vs. Gefitinib in Met. NSCLC With EGFR Ex 19 Deletion/L858R Mut | @JCO_ASCO I can’t keep up with all new EGFRi! @NarjustDumaMD @DrMarkAwad @CharuAggarwalMD https://t.co/q4IroZuBe9 (@DrChoueiri)
almost 2 years ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR L858R • EGFR exon 19 deletion
|
gefitinib • Ameile (aumolertinib)
almost2years
⭐️ Another new drug for EGFR ✅AUMOLERTINIB 👉🏼AENEAS: A Randomized Phase III Trial of Aumolertinib Versus Gefitinib as 1st-Line Therapy for Locally Advanced or Metastatic NSCLC With EGFR Exon 19 Deletion or L858R Mutations 🧬🎯@JCO_ASCO @OncoAlert https://t.co/ko2T8sUFLh (@VivekSubbiah)
almost 2 years ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR L858R • EGFR exon 19 deletion
|
gefitinib • Ameile (aumolertinib)
2years
First-line FDA-approved therapies for EGFR-sensitizing mutations like exon 19 deletions include osimertinib as the preferred frontline treatment, followed by erlotinib, gefitini, afatinib, and dacomitinib @ZPiotrowskaMD @MassGeneralNews #lcsm https://t.co/h29AI609Uz (@OncLive)
2 years ago
Clinical • FDA event
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR exon 19 deletion
|
Tagrisso (osimertinib) • erlotinib • Gilotrif (afatinib) • Vizimpro (dacomitinib)
2years
#TTLC22 Dr. @MJGrantMD presents outcomes with a specific subset of #EGFR exon 19 deletion NSCLC: L747-A750>P. Accounts for ~4% of del19. The proline insertion subset had a worse prognosis. Potential role for afatinib in this subset? Preclinical support; needs clinical validation. (@StephenVLiu)
2 years ago
EGFR (Epidermal growth factor receptor)
|
EGFR exon 19 deletion
|
Gilotrif (afatinib)
over2years
In most #EGFR NSCLC studies, exon 19 deletion associated with better outcomes than exon 21 L858R. This single center analysis explores co-mutations in tumor suppressor genes between the two. Could KEAP1 alterations be playing a role in EGFR mutant NSCLC? https://t.co/FTMW7hF1uV (@StephenVLiu)
over 2 years ago
Clinical
|
EGFR (Epidermal growth factor receptor) • KEAP1 (Kelch Like ECH Associated Protein 1)
|
EGFR mutation • EGFR L858R • EGFR exon 19 deletion • KEAP1 mutation
over2years
#ESMO21 #LCSM Ph2 WJOG9717L trial: osimertinib plus bevacizumab vs Osi for NSCLC with comm EGFR mut’s Subgroup analysis with better trend of PFS for OB: 🔹ex-smoker (HR 0.481) 🔹19del (HR 0.622) ▪️ORR: 82% vs 86% for O arm. 🔸G3/4 AEs: OB 56% vs O 48% for OB arm (@APassaroMD)
over 2 years ago
EGFR (Epidermal growth factor receptor)
|
EGFR exon 19 deletion
|
Avastin (bevacizumab) • Tagrisso (osimertinib)
over2years
#ESMO21 #LCSM Dr Piccirillo presenting thePh3 BEVERLY-trial: Italian random open-label, trial of bevacizumab (BEV) plus erlotinib (E) vs E alone as 1L treat for EGFR-mut a NSCLC. 180 pts random: 80 vs 80 55% of pts had ex19Del and 41% L858R mutation (@APassaroMD)
over 2 years ago
Clinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR L858R • EGFR exon 19 deletion
|
Avastin (bevacizumab) • erlotinib
almost3years
We have designed this session to be case-based & highly interactive. Hot topics like: “My patient with stage IV NSCLC and PD-L1 of 80% has already been started on checkpoint inhibitor elsewhere. Now molecular testing shows EGFR ex19del. YIKES!! What do I do now? Join us. (@drgandara)
almost 3 years ago
Clinical • Checkpoint inhibition
|
EGFR (Epidermal growth factor receptor) • PD-L1 (Programmed death ligand 1)
|
EGFR exon 19 deletion
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