Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
BIOMARKER:
EGFR L858R
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
›
Related tests:
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (21)
cobas® EGFR Mutation Test v2 (13)
therascreen® EGFR RGQ PCR Kit (5)
MI Cancer Seek™
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (21)
cobas® EGFR Mutation Test v2 (13)
therascreen® EGFR RGQ PCR Kit (5)
MI Cancer Seek™
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
afatinib
Sensitive: A1 - Approval
afatinib
Sensitive
:
A1
afatinib
Sensitive: A1 - Approval
afatinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
dacomitinib
Sensitive: A1 - Approval
dacomitinib
Sensitive
:
A1
dacomitinib
Sensitive: A1 - Approval
dacomitinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
gefitinib
Sensitive: A1 - Approval
gefitinib
Sensitive
:
A1
gefitinib
Sensitive: A1 - Approval
gefitinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
erlotinib
Sensitive: A1 - Approval
erlotinib
Sensitive
:
A1
erlotinib
Sensitive: A1 - Approval
erlotinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
erlotinib + ramucirumab
Sensitive: A1 - Approval
erlotinib + ramucirumab
Sensitive
:
A1
erlotinib + ramucirumab
Sensitive: A1 - Approval
erlotinib + ramucirumab
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
bevacizumab + erlotinib
Sensitive: A2 - Guideline
bevacizumab + erlotinib
Sensitive
:
A2
bevacizumab + erlotinib
Sensitive: A2 - Guideline
bevacizumab + erlotinib
Sensitive
:
A2
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
gefitinib
Sensitive: A2 - Guideline
gefitinib
Sensitive
:
A2
gefitinib
Sensitive: A2 - Guideline
gefitinib
Sensitive
:
A2
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
icotinib
Sensitive: B - Late Trials
icotinib
Sensitive
:
B
icotinib
Sensitive: B - Late Trials
icotinib
Sensitive
:
B
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
gefitinib + rivoceranib
Sensitive: B - Late Trials
gefitinib + rivoceranib
Sensitive
:
B
gefitinib + rivoceranib
Sensitive: B - Late Trials
gefitinib + rivoceranib
Sensitive
:
B
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
bevacizumab + atezolizumab
Sensitive: B - Late Trials
bevacizumab + atezolizumab
Sensitive
:
B
bevacizumab + atezolizumab
Sensitive: B - Late Trials
bevacizumab + atezolizumab
Sensitive
:
B
EGFR L858R
Lung Adenocarcinoma
EGFR L858R
Lung Adenocarcinoma
gefitinib
Sensitive: B - Late Trials
gefitinib
Sensitive
:
B
gefitinib
Sensitive: B - Late Trials
gefitinib
Sensitive
:
B
EGFR L858R
Lung Adenocarcinoma
EGFR L858R
Lung Adenocarcinoma
erlotinib
Resistant: B - Late Trials
erlotinib
Resistant
:
B
erlotinib
Resistant: B - Late Trials
erlotinib
Resistant
:
B
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
gefitinib + ramucirumab
Sensitive: B - Late Trials
gefitinib + ramucirumab
Sensitive
:
B
gefitinib + ramucirumab
Sensitive: B - Late Trials
gefitinib + ramucirumab
Sensitive
:
B
EGFR L858R
Lung Non-Small Cell Squamous Cancer
EGFR L858R
Lung Non-Small Cell Squamous Cancer
erlotinib
Sensitive: B - Late Trials
erlotinib
Sensitive
:
B
erlotinib
Sensitive: B - Late Trials
erlotinib
Sensitive
:
B
EGFR L858R
Lung Non-Small Cell Squamous Cancer
EGFR L858R
Lung Non-Small Cell Squamous Cancer
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
aumolertinib
Sensitive: B - Late Trials
aumolertinib
Sensitive
:
B
aumolertinib
Sensitive: B - Late Trials
aumolertinib
Sensitive
:
B
EGFR L858R
Lung Adenocarcinoma
EGFR L858R
Lung Adenocarcinoma
afatinib
Sensitive: B - Late Trials
afatinib
Sensitive
:
B
afatinib
Sensitive: B - Late Trials
afatinib
Sensitive
:
B
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
firmonertinib
Sensitive: B - Late Trials
firmonertinib
Sensitive
:
B
firmonertinib
Sensitive: B - Late Trials
firmonertinib
Sensitive
:
B
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
lazertinib
Sensitive: B - Late Trials
lazertinib
Sensitive
:
B
lazertinib
Sensitive: B - Late Trials
lazertinib
Sensitive
:
B
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
befotertinib
Sensitive: B - Late Trials
befotertinib
Sensitive
:
B
befotertinib
Sensitive: B - Late Trials
befotertinib
Sensitive
:
B
EGFR L858R
Thyroid Gland Anaplastic Carcinoma
EGFR L858R
Thyroid Gland Anaplastic Carcinoma
erlotinib
Sensitive: C1 - Off-label
erlotinib
Sensitive
:
C1
erlotinib
Sensitive: C1 - Off-label
erlotinib
Sensitive
:
C1
EGFR L858R
Lung Adenocarcinoma
EGFR L858R
Lung Adenocarcinoma
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
EGFR L858R
Lung Cancer
EGFR L858R
Lung Cancer
osimertinib
Resistant: C1 - Off-label
osimertinib
Resistant
:
C1
osimertinib
Resistant: C1 - Off-label
osimertinib
Resistant
:
C1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
bevacizumab
Sensitive: C2 – Inclusion Criteria
bevacizumab
Sensitive
:
C2
bevacizumab
Sensitive: C2 – Inclusion Criteria
bevacizumab
Sensitive
:
C2
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
osimertinib + ABT 263
Sensitive: C2 – Inclusion Criteria
osimertinib + ABT 263
Sensitive
:
C2
osimertinib + ABT 263
Sensitive: C2 – Inclusion Criteria
osimertinib + ABT 263
Sensitive
:
C2
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
osimertinib + gefitinib
Sensitive: C2 – Inclusion Criteria
osimertinib + gefitinib
Sensitive
:
C2
osimertinib + gefitinib
Sensitive: C2 – Inclusion Criteria
osimertinib + gefitinib
Sensitive
:
C2
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
anlotinib + icotinib
Sensitive: C2 – Inclusion Criteria
anlotinib + icotinib
Sensitive
:
C2
anlotinib + icotinib
Sensitive: C2 – Inclusion Criteria
anlotinib + icotinib
Sensitive
:
C2
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login