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BIOMARKER:
EGFR exon 21 mutation
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
erlotinib + ramucirumab
Sensitive: B - Late Trials
erlotinib + ramucirumab
Sensitive
:
B
erlotinib + ramucirumab
Sensitive: B - Late Trials
erlotinib + ramucirumab
Sensitive
:
B
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
icotinib
Sensitive: B - Late Trials
icotinib
Sensitive
:
B
icotinib
Sensitive: B - Late Trials
icotinib
Sensitive
:
B
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
gefitinib
Sensitive: C2 – Inclusion Criteria
gefitinib
Sensitive
:
C2
gefitinib
Sensitive: C2 – Inclusion Criteria
gefitinib
Sensitive
:
C2
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
erlotinib
Sensitive: C2 – Inclusion Criteria
erlotinib
Sensitive
:
C2
erlotinib
Sensitive: C2 – Inclusion Criteria
erlotinib
Sensitive
:
C2
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
erlotinib + anlotinib
Sensitive: C3 – Early Trials
erlotinib + anlotinib
Sensitive
:
C3
erlotinib + anlotinib
Sensitive: C3 – Early Trials
erlotinib + anlotinib
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
EGFR exon 21 mutation
Lung Adenocarcinoma
EGFR exon 21 mutation
Lung Adenocarcinoma
erlotinib
Sensitive: C3 – Early Trials
erlotinib
Sensitive
:
C3
erlotinib
Sensitive: C3 – Early Trials
erlotinib
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
dacomitinib
Sensitive: C3 – Early Trials
dacomitinib
Sensitive
:
C3
dacomitinib
Sensitive: C3 – Early Trials
dacomitinib
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
Tyrosine kinase inhibitor
Sensitive: C3 – Early Trials
Tyrosine kinase inhibitor
Sensitive
:
C3
Tyrosine kinase inhibitor
Sensitive: C3 – Early Trials
Tyrosine kinase inhibitor
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
afatinib
Sensitive: C3 – Early Trials
afatinib
Sensitive
:
C3
afatinib
Sensitive: C3 – Early Trials
afatinib
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
durvalumab
Sensitive: C3 – Early Trials
durvalumab
Sensitive
:
C3
durvalumab
Sensitive: C3 – Early Trials
durvalumab
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
FCN-411
Sensitive: C3 – Early Trials
FCN-411
Sensitive
:
C3
FCN-411
Sensitive: C3 – Early Trials
FCN-411
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
bevacizumab + osimertinib
Resistant: C3 – Early Trials
bevacizumab + osimertinib
Resistant
:
C3
bevacizumab + osimertinib
Resistant: C3 – Early Trials
bevacizumab + osimertinib
Resistant
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
pembrolizumab
Sensitive: C3 – Early Trials
pembrolizumab
Sensitive
:
C3
pembrolizumab
Sensitive: C3 – Early Trials
pembrolizumab
Sensitive
:
C3
EGFR exon 21 mutation
Lung Adenocarcinoma
EGFR exon 21 mutation
Lung Adenocarcinoma
osimertinib
Sensitive: C3 – Early Trials
osimertinib
Sensitive
:
C3
osimertinib
Sensitive: C3 – Early Trials
osimertinib
Sensitive
:
C3
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR exon 21 mutation
Non Small Cell Lung Cancer
EGFR inhibitor
Sensitive: C3 – Early Trials
EGFR inhibitor
Sensitive
:
C3
EGFR inhibitor
Sensitive: C3 – Early Trials
EGFR inhibitor
Sensitive
:
C3
EGFR exon 21 mutation
Small Cell Lung Cancer
EGFR exon 21 mutation
Small Cell Lung Cancer
gefitinib
Sensitive: C4 – Case Studies
gefitinib
Sensitive
:
C4
gefitinib
Sensitive: C4 – Case Studies
gefitinib
Sensitive
:
C4
EGFR exon 21 mutation
Lung Adenocarcinoma
EGFR exon 21 mutation
Lung Adenocarcinoma
dacomitinib
Sensitive: C4 – Case Studies
dacomitinib
Sensitive
:
C4
dacomitinib
Sensitive: C4 – Case Studies
dacomitinib
Sensitive
:
C4
EGFR exon 21 mutation
Lung Adenocarcinoma
EGFR exon 21 mutation
Lung Adenocarcinoma
aumolertinib
Sensitive: C4 – Case Studies
aumolertinib
Sensitive
:
C4
aumolertinib
Sensitive: C4 – Case Studies
aumolertinib
Sensitive
:
C4
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