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BIOMARKER:
EGFR exon 19 deletion
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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News alerts, weekly reports and conference planners
Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
›
Related tests:
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (19)
cobas® EGFR Mutation Test v2 (13)
Oncomine™ Dx Target Test (10)
therascreen® EGFR RGQ PCR Kit (5)
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (19)
cobas® EGFR Mutation Test v2 (13)
Oncomine™ Dx Target Test (10)
therascreen® EGFR RGQ PCR Kit (5)
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
Associations
News
Trials
VERI cancer hierarchy
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EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
afatinib
Sensitive: A1 - Approval
Thorac Cancer - 6 days (New C3)
afatinib
Sensitive
:
A1
Thorac Cancer - 6d
afatinib
Sensitive: A1 - Approval
Thorac Cancer - 6 days
afatinib
Sensitive
:
A1
Thorac Cancer - 6 days - (New C3)
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
erlotinib
Sensitive: A1 - Approval
Thorac Cancer - 6 days (New C3)
erlotinib
Sensitive
:
A1
Thorac Cancer - 6d
erlotinib
Sensitive: A1 - Approval
Thorac Cancer - 6 days
erlotinib
Sensitive
:
A1
Thorac Cancer - 6 days - (New C3)
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
AZD3759
Sensitive: C3 – Early Trials
EClinicalMedicine - 1 week (New C3)
AZD3759
Sensitive
:
C3
EClinicalMedicine - 1wk
AZD3759
Sensitive: C3 – Early Trials
EClinicalMedicine - 1 week
AZD3759
Sensitive
:
C3
EClinicalMedicine - 1 week - (New C3)
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: B - Late Trials
Nat Med - 2 weeks (New C3)
amivantamab-vmjw + lazertinib
Sensitive
:
B
Nat Med - 2wk
amivantamab-vmjw + lazertinib
Sensitive: B - Late Trials
Nat Med - 2 weeks
amivantamab-vmjw + lazertinib
Sensitive
:
B
Nat Med - 2 weeks - (New C3)
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
lazertinib
Sensitive: B - Late Trials
J Thorac Oncol - 2 weeks (New B)
lazertinib
Sensitive
:
B
J Thorac Oncol - 2wk
lazertinib
Sensitive: B - Late Trials
J Thorac Oncol - 2 weeks
lazertinib
Sensitive
:
B
J Thorac Oncol - 2 weeks - (New B)
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
U3-1402
Sensitive: C2 – Inclusion Criteria
J Clin Oncol - 2 weeks (New C3)
U3-1402
Sensitive
:
C2
J Clin Oncol - 2wk
U3-1402
Sensitive: C2 – Inclusion Criteria
J Clin Oncol - 2 weeks
U3-1402
Sensitive
:
C2
J Clin Oncol - 2 weeks - (New C3)
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: B - Late Trials
J&J Press Release - 3 weeks (New B)
amivantamab-vmjw
Sensitive
:
B
J&J Press Release - 3wk
amivantamab-vmjw
Sensitive: B - Late Trials
J&J Press Release - 3 weeks
amivantamab-vmjw
Sensitive
:
B
J&J Press Release - 3 weeks - (New B)
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
gefitinib
Sensitive: A1 - Approval
gefitinib
Sensitive
:
A1
gefitinib
Sensitive: A1 - Approval
gefitinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
dacomitinib
Sensitive: A1 - Approval
dacomitinib
Sensitive
:
A1
dacomitinib
Sensitive: A1 - Approval
dacomitinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
erlotinib + ramucirumab
Sensitive: A1 - Approval
erlotinib + ramucirumab
Sensitive
:
A1
erlotinib + ramucirumab
Sensitive: A1 - Approval
erlotinib + ramucirumab
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
bevacizumab + erlotinib
Sensitive: A2 - Guideline
bevacizumab + erlotinib
Sensitive
:
A2
bevacizumab + erlotinib
Sensitive: A2 - Guideline
bevacizumab + erlotinib
Sensitive
:
A2
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR exon 19 deletion
Lung Adenocarcinoma
EGFR exon 19 deletion
Lung Adenocarcinoma
gefitinib
Sensitive: B - Late Trials
gefitinib
Sensitive
:
B
gefitinib
Sensitive: B - Late Trials
gefitinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
icotinib
Sensitive: B - Late Trials
icotinib
Sensitive
:
B
icotinib
Sensitive: B - Late Trials
icotinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
gefitinib + rivoceranib
Sensitive: B - Late Trials
gefitinib + rivoceranib
Sensitive
:
B
gefitinib + rivoceranib
Sensitive: B - Late Trials
gefitinib + rivoceranib
Sensitive
:
B
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
bevacizumab + atezolizumab
Sensitive: B - Late Trials
bevacizumab + atezolizumab
Sensitive
:
B
bevacizumab + atezolizumab
Sensitive: B - Late Trials
bevacizumab + atezolizumab
Sensitive
:
B
EGFR exon 19 deletion
Lung Adenocarcinoma
EGFR exon 19 deletion
Lung Adenocarcinoma
afatinib
Sensitive: B - Late Trials
afatinib
Sensitive
:
B
afatinib
Sensitive: B - Late Trials
afatinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
gefitinib + ramucirumab
Sensitive: B - Late Trials
gefitinib + ramucirumab
Sensitive
:
B
gefitinib + ramucirumab
Sensitive: B - Late Trials
gefitinib + ramucirumab
Sensitive
:
B
EGFR exon 19 deletion
Lung Non-Small Cell Squamous Cancer
EGFR exon 19 deletion
Lung Non-Small Cell Squamous Cancer
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
aumolertinib
Sensitive: B - Late Trials
aumolertinib
Sensitive
:
B
aumolertinib
Sensitive: B - Late Trials
aumolertinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
furmonertinib
Sensitive: B - Late Trials
furmonertinib
Sensitive
:
B
furmonertinib
Sensitive: B - Late Trials
furmonertinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
befotertinib
Sensitive: B - Late Trials
befotertinib
Sensitive
:
B
befotertinib
Sensitive: B - Late Trials
befotertinib
Sensitive
:
B
EGFR exon 19 deletion
Lung Adenocarcinoma
EGFR exon 19 deletion
Lung Adenocarcinoma
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
EGFR exon 19 deletion
Small Cell Lung Cancer
EGFR exon 19 deletion
Small Cell Lung Cancer
gefitinib
Sensitive: C1 - Off-label
gefitinib
Sensitive
:
C1
gefitinib
Sensitive: C1 - Off-label
gefitinib
Sensitive
:
C1
EGFR exon 19 deletion
Lung Cancer
EGFR exon 19 deletion
Lung Cancer
gefitinib
Sensitive: C1 - Off-label
gefitinib
Sensitive
:
C1
gefitinib
Sensitive: C1 - Off-label
gefitinib
Sensitive
:
C1
EGFR exon 19 deletion
Small Cell Lung Cancer
EGFR exon 19 deletion
Small Cell Lung Cancer
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
osimertinib + gefitinib
Sensitive: C2 – Inclusion Criteria
osimertinib + gefitinib
Sensitive
:
C2
osimertinib + gefitinib
Sensitive: C2 – Inclusion Criteria
osimertinib + gefitinib
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
anlotinib + icotinib
Sensitive: C2 – Inclusion Criteria
anlotinib + icotinib
Sensitive
:
C2
anlotinib + icotinib
Sensitive: C2 – Inclusion Criteria
anlotinib + icotinib
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGF816
Sensitive: C2 – Inclusion Criteria
EGF816
Sensitive
:
C2
EGF816
Sensitive: C2 – Inclusion Criteria
EGF816
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
bevacizumab + osimertinib
Sensitive: C2 – Inclusion Criteria
bevacizumab + osimertinib
Sensitive
:
C2
bevacizumab + osimertinib
Sensitive: C2 – Inclusion Criteria
bevacizumab + osimertinib
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
tislelizumab
Sensitive: C2 – Inclusion Criteria
tislelizumab
Sensitive
:
C2
tislelizumab
Sensitive: C2 – Inclusion Criteria
tislelizumab
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
durvalumab
Sensitive: C2 – Inclusion Criteria
durvalumab
Sensitive
:
C2
durvalumab
Sensitive: C2 – Inclusion Criteria
durvalumab
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
bevacizumab
Sensitive: C2 – Inclusion Criteria
bevacizumab
Sensitive
:
C2
bevacizumab
Sensitive: C2 – Inclusion Criteria
bevacizumab
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
BBT-176
Sensitive: C2 – Inclusion Criteria
BBT-176
Sensitive
:
C2
BBT-176
Sensitive: C2 – Inclusion Criteria
BBT-176
Sensitive
:
C2
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
anlotinib + icotinib
Sensitive: C2 – Inclusion Criteria
anlotinib + icotinib
Sensitive
:
C2
anlotinib + icotinib
Sensitive: C2 – Inclusion Criteria
anlotinib + icotinib
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
anlotinib + aumolertinib
Sensitive: C2 – Inclusion Criteria
anlotinib + aumolertinib
Sensitive
:
C2
anlotinib + aumolertinib
Sensitive: C2 – Inclusion Criteria
anlotinib + aumolertinib
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
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