TEST:

VENTANA® TROP2 (EPR20043) RxDx Assay

The VENTANA® TROP2 (EPR20043) RxDx Assay is an FDA-approved immunohistochemistry (IHC) companion diagnostic developed by Roche Tissue Diagnostics. It is designed to detect the expression of TROP2 (Trophoblast Cell Surface Antigen 2) protein in formalin-fixed, paraffin-embedded (FFPE) tumor tissue samples. This assay utilizes the EPR20043 antibody to identify patients who may be eligible for TROP2-targeted therapies, such as antibody-drug conjugates like datopotamab deruxtecan.