IDH1 R132H (MRQ-67) Rabbit Monoclonal Antibody can detect the IDH1 R132H mutation in adult-type gliomas and in acute myeloid leukaemia (AML). When present, IDH1 R132H is associated with a relatively favourable prognosis and is important in patient stratification for clinical trials. IDH1 R132H immunohistochemistry is recommended by all major glioma clinical practice guidelines as the initial IDH testing modality.