^
Contact us  to learn more about
our Premium Content:  News alerts, weekly reports and conference planners

TEST:
Ventana MMR RxDx Panel

Company:
Roche
Type:
FDA Approved
Related tests:
Evidence Level:
Sensitive: A1 - Approval

[MSI-H/dMMR-Solid Tumor-pembrolizumab]

Source:
Published date:
03/29/2023
Excerpt:
KEYTRUDA is a programmed death receptor-1 (PD-1)-blocking antibody indicated:…for the treatment of adult and pediatric patients with unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) solid tumors, as determined by an FDA-approved test, that have progressed following prior treatment and who have no satisfactory alternative treatment options.
Evidence Level:
Sensitive: A1 - Approval

[MSI-H/dMMR-Endometrial Cancer-dostarlimab-gxly]

Source:
Published date:
02/09/2023
Excerpt:
JEMPERLI is a programmed death receptor-1 (PD-1)–blocking antibody indicated for the treatment of adult patients with mismatch repair deficient (dMMR) recurrent or advanced endometrial cancer, as determined by an FDA-approved test, that has progressed on or following prior treatment with a platinum-containing regimen in any setting and are not candidates for curative surgery or radiation.
Evidence Level:
Sensitive: A1 - Approval

[MSI-H/dMMR-Endometrial Cancer-pembrolizumab]

Source:
Published date:
03/22/2022
Excerpt:
KEYTRUDA is a programmed death receptor-1 (PD-1)-blocking antibody indicated...as a single agent, for the treatment of patients with advanced endometrial carcinoma that is MSI-H or dMMR, as determined by an FDA-approved test, who have disease progression following prior systemic therapy in any setting and are not candidates for curative surgery or radiation.
Evidence Level:
Sensitive: A1 - Approval

[MSI-H/dMMR-Solid Tumor-dostarlimab-gxly]

Source:
Published date:
08/17/2021
Excerpt:
JEMPERLI is a programmed death receptor-1 (PD-1)–blocking antibody indicated for the treatment of adult patients with mismatch repair deficient (dMMR) recurrent or advanced...solid tumors, as determined by an FDA-approved test, that have progressed on or following prior treatment and who have no satisfactory alternative treatment options.