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    TEST:
    VENTANA ALK (D5F3) CDx Assay

    Company:
    Roche
    Type:
    FDA Approved (PMA)
    Related tests:
    almost5years
    "M/48y Non smoker ECOG 0 Lung Adeno. Stg4 Denovo - Coexisting ALK + (D5F3) + EGFR exon 20 ins. Rx ? Sequence( which 1st) or combine ? Which EGFR Rx - Td-m1 or TKI ? Which ALK TKI ? Any role of Brigatinib ? @LeciaSequist @geoff_oxnard @PatelOncology @StephenVLiu @DrSteveMartin" (@oncologician)
    EGFR (Epidermal growth factor receptor)
    |
    EGFR exon 20 insertion • EGFR exon 20 mutation
    |
    VENTANA ALK (D5F3) CDx Assay
    |
    Alunbrig (brigatinib)
    5years
    "1️⃣Lorlatinib 2️⃣clinical trial 3️⃣Platin based chemo +/- ICI (KN189 or CM9La schedule) Identify concomitant mut’s using NGS it is quite common, at the moment w/out a specific clinical value! Working progress 👉🏻In CROWN & ALEX,ALK was determined by Ventana D5F3 IHC assay! #LCSM" (@APassaroMD)
    Clinical
    |
    VENTANA ALK (D5F3) CDx Assay
    |
    Lorbrena (lorlatinib)
    over5years
    "Don’t know for ALCL but D5F3 (ultrasensitive) is great for IMT and NSCLC" (@smlungpathguy)
    VENTANA ALK (D5F3) CDx Assay
    7years
    "Inflammatory myofibroblastic tumor. ALK (D5F3)" (@mufster82)
    VENTANA ALK (D5F3) CDx Assay