The oncoReveal 4 Gene Methylation Panel is a robust NGS assay that interrogates CpG sites within BRCA1, BRCA2, RAD51C, and XRCC3 that have undergone bisulfite conversion for methylome analysis. The assay uses proprietary Stem-Loop Inhibition-Mediated amplification (SLIMamp®) technology, a tiled amplicon-based library prep chemistry for efficient single-tube enrichment of targets.
Cancer:
Breast Cancer
Gene:
BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), RAD51C (RAD51 paralog C), XRCC3 (X-Ray Repair Cross Complementing 3)
BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), RAD51C (RAD51 paralog C), XRCC3 (X-Ray Repair Cross Complementing 3)