TEST:

FoundationOne®RNA

F1R assay successfully detected oncogenic fusions with high concordance to orthogonal NGS-based tests. This study demonstrated the robustness of F1R and supports its use as a supplement to tissue DNA CGP in routine clinical practice. Additional work is required to clarify optimal clinical scenarios for fusion detection and enable GEP biomarkers for clinical use.

"Foundation Medicine Inc...announced the launch of the research use and investigational use versions of FoundationOne®RNA, its broad tissue-based RNA test. While DNA sequencing with optimized targeting can detect most fusions, FoundationOne RNA can provide another layer of sophisticated fusion detection in 318 genes through RNA sequencing."