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DRUG:
PF-08046052
i
Other names:
PF-08046052, SGN-EGFRd2, LAVA-1223, LAVA-224×223, LAVA1223, LAVA224×223, PF08046052, LAVA 1223, LAVA 224×223, PF 08046052
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Associations
News
Trials
Company:
LAVA Therap, Pfizer
Drug class:
EGFR inhibitor, γδ TCR modulator
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afatinib (227)
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lapatinib (107)
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pyrotinib (79)
brigatinib (50)
icotinib (45)
aumolertinib (39)
amivantamab-vmjw (25)
firmonertinib (14)
mobocertinib (12)
lazertinib (12)
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ADI-001 (1)
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autologous γδ T lymphocytes (0)
ALEXIS-ISO-1 (0)
LAVA-051 (0)
LYT-210 (0)
NK/γδ T cell-enriched cell therapy (0)
QH104 (0)
TAK-012 (0)
UTAA06 (0)
anti-CD19-CAR γδT (0)
AVM0703 (0)
γδT Cell infusion (0)
γδT Cell infusion agent (0)
cetuximab (347)
osimertinib (301)
erlotinib (235)
afatinib (227)
gefitinib (194)
panitumumab (123)
lapatinib (107)
neratinib (102)
pyrotinib (79)
brigatinib (50)
icotinib (45)
aumolertinib (39)
amivantamab-vmjw (25)
firmonertinib (14)
mobocertinib (12)
lazertinib (12)
BGB-283 (12)
tarloxotinib bromide (7)
WZ4002 (7)
CH7233163 (6)
H002 (6)
nimotuzumab (6)
BLU-945 (6)
ASLAN001 (6)
BBT-176 (5)
CL-387785 (5)
GB263T (5)
rociletinib (5)
BDTX-189 (5)
AEE788 (4)
BDTX-1535 (4)
BI-4020 (4)
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MET306 (4)
EGF816 (4)
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BLU-701 (3)
GC-1118A (3)
MCLA-129 (3)
necitumumab (3)
befotertinib (3)
BCA101 (3)
S95026 (3)
ASP8273 (3)
DZD9008 (3)
SZMD4 (3)
AZD3759 (3)
ACE2016 (2)
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BLU-451 (2)
Bay846 (2)
ERAS-801 (2)
OBX02-011 (2)
olmutinib (2)
QL1203 (2)
CLN-081 (2)
14aj (1)
ABN202 (1)
ABP 494 (cetuximab biosimilar) (1)
APL-103 (1)
BAY 2927088 (1)
BPI-15086 (1)
BPI-361175 (1)
Compound 6a (1)
abivertinib (1)
KKI04 (1)
PH001 (1)
rilertinib (1)
TAS3351 (1)
TRX-221 (1)
WSD0922 (1)
JMT101 (1)
S-222611 (1)
HMPL-813 (1)
SI-B001 (1)
ASK120067 (1)
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ABT-101 (0)
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BBT-207 (0)
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CM93 (0)
CUDC-101 (0)
EGF-PTI (0)
DF9001 (0)
DK210 (0)
STI-001 (cetuximab biosimilar) (0)
FHND9041 (0)
HLX35 (0)
HS-10375 (0)
antroquinonol (0)
zalutumumab (0)
IAE0972 (0)
IBI-334 (0)
JANX008 (0)
JNJ-26483327 (0)
JS111 (0)
MM-151 (0)
MP412 (0)
MTX-211 (0)
PLB1004 (0)
PM1080 (0)
QLH11811 (0)
rindopepimut (0)
SR13668 (0)
SYN004 (0)
Sym013 (0)
TAK-186 (0)
TAK-285 (0)
TAS-121 (0)
TAVO412 (0)
THE-349 (0)
TQ-B3456 (0)
TQB3804 (0)
U3-1565 (0)
Undisclosed EGFR inhibitor (0)
XZP-5809 (0)
simotinib (0)
ZN-e4 (0)
AST1306 (0)
SY101 (0)
Ami-LC (0)
TY-9591 (0)
EMB-01 (0)
cetuximab biosimilar (0)
cipatinib (0)
ABT-806 (0)
MEHD7945A (0)
RO5083945 (0)
TL007 (0)
EMD 72000 (0)
PF-06747775 (0)
JNJ-64041757 (0)
KBP-5209 (0)
SKLB-1028 (0)
AZD8931 (0)
Undisclosed allogeneic Vγ9Vδ2 HER2-TAC T (4)
ADI-001 (1)
ACE1831 (0)
ADI-002 (0)
BTN2A1/3A1-Fc-CD19scFv (0)
CD7-UCAR-γδT cells (0)
CLN-619 (0)
CTM-N2D (0)
ECT204 (0)
ET 019003 (0)
ET-190 (0)
ET140203 (0)
ET1402L1-ARTEMIS T cells (0)
ET206 (0)
GDT002 (0)
Gamma delta T-cells (0)
ICT01 (0)
INB-100 (0)
INB-200 (0)
INB-300 (0)
autologous γδ T lymphocytes (0)
ALEXIS-ISO-1 (0)
LAVA-051 (0)
LYT-210 (0)
NK/γδ T cell-enriched cell therapy (0)
QH104 (0)
TAK-012 (0)
UTAA06 (0)
anti-CD19-CAR γδT (0)
AVM0703 (0)
γδT Cell infusion (0)
γδT Cell infusion agent (0)
›
Associations
News
Trials
Filter by
Latest
1year
A Study of SGN-EGFRd2 in Advanced Solid Tumors (clinicaltrials.gov)
P1, N=275, Recruiting, Seagen Inc. | Not yet recruiting --> Recruiting
1 year ago
Enrollment open • Metastases
|
EGFR (Epidermal growth factor receptor) • ALK (Anaplastic lymphoma kinase) • MSI (Microsatellite instability)
|
EGFR mutation • MSI-H/dMMR • ALK rearrangement • EGFR rearrangement
|
PF-08046052
over1year
A Study of SGN-EGFRd2 in Advanced Solid Tumors (clinicaltrials.gov)
P1, N=275, Not yet recruiting, Seagen Inc.
over 1 year ago
New P1 trial • Metastases
|
EGFR (Epidermal growth factor receptor) • ALK (Anaplastic lymphoma kinase) • MSI (Microsatellite instability)
|
EGFR mutation • MSI-H/dMMR • ALK rearrangement • EGFR rearrangement
|
PF-08046052
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