^
Contact us  to learn more about
our Premium Content:  News alerts, weekly reports and conference planners
DRUG:

CL-387785

i
Other names: WAY-EKI 785, CL-387785, EKI-785, CL 387785
Company:
Pfizer
Drug class:
EGFR inhibitor
Related drugs:
over1year
Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR/PI3K/AKT pathway. (PubMed, Int J Oncol)
Exo‑si‑PYCR1 blocked xenograft tumor growth and had good biocompatibility. Briefly, PYCR1 knocking loaded by BMSC‑derived Exos suppressed aerobic glycolysis and BC growth via the PI3K/AKT pathway by binding to EGFR.
Journal
|
PRO-C3 (Pyrroline-5-carboxylate reductase)
|
CL-387785