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GENE:
NFE2L2 (Nuclear Factor, Erythroid 2 Like 2)
i
Other names:
NFE2L2, Nuclear Factor Erythroid 2 Like 2, Nuclear Factor Erythroid 2-Related Factor 2, NF-E2-Related Factor 2, HEBP1, Nrf-2, NRF2, Nuclear Factor Erythroid Derived 2 Like 2, Nuclear Factor (Erythroid-Derived 2)-Like 2, Nuclear Factor Erythroid-Derived 2-Like 2, Nuclear Factor Erythroid 2-Like 2, NFE2-Related Factor 2, IMDDHH
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Entrez ID:
4780
Related tests:
‹
Guardant360® CDx (54)
Guardant360 TissueNext™ (2)
AmoyDx® HANDLE Classic NGS Panel
InVisionSeq™
NeoTYPE® Lung Tumor Profile
OncoGuide™ NCC Oncopanel System
oncoReveal™ Core LBx
Guardant360® CDx (54)
Guardant360 TissueNext™ (2)
AmoyDx® HANDLE Classic NGS Panel
InVisionSeq™
NeoTYPE® Lung Tumor Profile
OncoGuide™ NCC Oncopanel System
oncoReveal™ Core LBx
›
Associations
(14)
News
Trials
VERI cancer hierarchy
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NFE2L2 mutation + STK11 mutation
Non Small Cell Lung Cancer
NFE2L2 mutation + STK11 mutation
Non Small Cell Lung Cancer
DRP-104
Sensitive: B - Late Trials
DRP-104
Sensitive
:
B
DRP-104
Sensitive: B - Late Trials
DRP-104
Sensitive
:
B
NFE2L2 mutation
Non Small Cell Lung Cancer
NFE2L2 mutation
Non Small Cell Lung Cancer
DRP-104
Sensitive: B - Late Trials
DRP-104
Sensitive
:
B
DRP-104
Sensitive: B - Late Trials
DRP-104
Sensitive
:
B
NFE2L2 mutation
Lung Non-Small Cell Squamous Cancer
NFE2L2 mutation
Lung Non-Small Cell Squamous Cancer
CB-228
Sensitive: B - Late Trials
CB-228
Sensitive
:
B
CB-228
Sensitive: B - Late Trials
CB-228
Sensitive
:
B
NFE2L2 mutation
Solid Tumor
NFE2L2 mutation
Solid Tumor
IPN60090
Sensitive: C2 – Inclusion Criteria
IPN60090
Sensitive
:
C2
IPN60090
Sensitive: C2 – Inclusion Criteria
IPN60090
Sensitive
:
C2
NFE2L2 mutation
Lung Cancer
NFE2L2 mutation
Lung Cancer
IPN60090
Sensitive: C2 – Inclusion Criteria
IPN60090
Sensitive
:
C2
IPN60090
Sensitive: C2 – Inclusion Criteria
IPN60090
Sensitive
:
C2
NFE2L2 mutation
Lung Cancer
NFE2L2 mutation
Lung Cancer
CB-228
Sensitive: C2 – Inclusion Criteria
CB-228
Sensitive
:
C2
CB-228
Sensitive: C2 – Inclusion Criteria
CB-228
Sensitive
:
C2
NFE2L2 mutation
Non Small Cell Lung Cancer
NFE2L2 mutation
Non Small Cell Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
NFE2L2 E79K
Lung Non-Small Cell Squamous Cancer
NFE2L2 E79K
Lung Non-Small Cell Squamous Cancer
CB-228
Sensitive: C3 – Early Trials
CB-228
Sensitive
:
C3
CB-228
Sensitive: C3 – Early Trials
CB-228
Sensitive
:
C3
NFE2L2 overexpression
Hepatocellular Cancer
NFE2L2 overexpression
Hepatocellular Cancer
sorafenib
Resistant: C3 – Early Trials
sorafenib
Resistant
:
C3
sorafenib
Resistant: C3 – Early Trials
sorafenib
Resistant
:
C3
NFE2L2 mutation
Lung Non-Small Cell Squamous Cancer
NFE2L2 mutation
Lung Non-Small Cell Squamous Cancer
CB-228 + CB-839
Sensitive: C3 – Early Trials
CB-228 + CB-839
Sensitive
:
C3
CB-228 + CB-839
Sensitive: C3 – Early Trials
CB-228 + CB-839
Sensitive
:
C3
NFE2L2 overexpression
Acute Myelogenous Leukemia
NFE2L2 overexpression
Acute Myelogenous Leukemia
cytarabine
Resistant: D – Preclinical
cytarabine
Resistant
:
D
cytarabine
Resistant: D – Preclinical
cytarabine
Resistant
:
D
NFE2L2 mutation + CTNNB1 mutation
Hepatocellular Cancer
NFE2L2 mutation + CTNNB1 mutation
Hepatocellular Cancer
everolimus
Sensitive: D – Preclinical
everolimus
Sensitive
:
D
everolimus
Sensitive: D – Preclinical
everolimus
Sensitive
:
D
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