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BIOMARKER:
IDH1 R132H
i
Other names:
HEL-216, HEL-S-26, Epididymis Luminal Protein 216, Isocitrate Dehydrogenase 1 (NADP+), Epididymis Secretory Protein Li 26, IDH1, Isocitrate Dehydrogenase (NADP(+)) 1, Isocitrate Dehydrogenase 1 (NADP+), Soluble
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Entrez ID:
3417
Related biomarkers:
Expression
Mutation
Others
‹
IDH1 mutation (79)
IDH1 R132C (5)
IDH wild-type (3)
IDH1 R132 (3)
FLT3-ITD mutation + IDH1 mutation (2)
IDH1 R132G (2)
IDH1 wild-type + BRAF mutation (2)
IDH1 wild-type + NF1 mutation (2)
DNMT3A mutation + IDH mutation (1)
EGFR L858R + IDH1 R132C (1)
EGFR mutation + IDH1 mutation (1)
EGFR mutation+ IDH1 R132H (1)
FLT3 mutation + IDH1 mutation (1)
IDH1 R132C + EGFR L861Q (1)
IDH1 R132C + IDH1 S280F (1)
IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)
IDH1 R132H + PTEN C78T (1)
IDH1 R132L (1)
IDH1 R132S (1)
IDH1 R132V (1)
IDH1 mutation + TP53 mutation (1)
IDH1 rs1437410 (1)
IDH mutation + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) (0)
IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)
IDH mutation + NTRK fusion (0)
IDH1 mutation (79)
IDH1 R132C (5)
IDH wild-type (3)
IDH1 R132 (3)
FLT3-ITD mutation + IDH1 mutation (2)
IDH1 R132G (2)
IDH1 wild-type + BRAF mutation (2)
IDH1 wild-type + NF1 mutation (2)
DNMT3A mutation + IDH mutation (1)
EGFR L858R + IDH1 R132C (1)
EGFR mutation + IDH1 mutation (1)
EGFR mutation+ IDH1 R132H (1)
FLT3 mutation + IDH1 mutation (1)
IDH1 R132C + EGFR L861Q (1)
IDH1 R132C + IDH1 S280F (1)
IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)
IDH1 R132H + PTEN C78T (1)
IDH1 R132L (1)
IDH1 R132S (1)
IDH1 R132V (1)
IDH1 mutation + TP53 mutation (1)
IDH1 rs1437410 (1)
IDH mutation + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) (0)
IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)
IDH mutation + NTRK fusion (0)
›
Related tests:
Abbott RealTime IDH1 (4)
Abbott RealTime IDH1 (4)
Associations
News
Trials
VERI cancer hierarchy
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IDH1 R132H
Anaplastic Astrocytoma
IDH1 R132H
Anaplastic Astrocytoma
temozolomide
Sensitive: B - Late Trials
temozolomide
Sensitive
:
B
temozolomide
Sensitive: B - Late Trials
temozolomide
Sensitive
:
B
IDH1 R132H
Acute Myelogenous Leukemia
IDH1 R132H
Acute Myelogenous Leukemia
dasatinib
Sensitive: C3 – Early Trials
dasatinib
Sensitive
:
C3
dasatinib
Sensitive: C3 – Early Trials
dasatinib
Sensitive
:
C3
IDH1 R132H
Acute Myelogenous Leukemia
IDH1 R132H
Acute Myelogenous Leukemia
midostaurin
Sensitive: C4 – Case Studies
midostaurin
Sensitive
:
C4
midostaurin
Sensitive: C4 – Case Studies
midostaurin
Sensitive
:
C4
IDH1 R132H
Glioma
IDH1 R132H
Glioma
PD-L1 inhibitor + IDH1 inhibitor
Sensitive: D – Preclinical
PD-L1 inhibitor + IDH1 inhibitor
Sensitive
:
D
PD-L1 inhibitor + IDH1 inhibitor
Sensitive: D – Preclinical
PD-L1 inhibitor + IDH1 inhibitor
Sensitive
:
D
IDH1 R132H
Glioma
IDH1 R132H
Glioma
olaparib + AZD6738
Sensitive: D – Preclinical
olaparib + AZD6738
Sensitive
:
D
olaparib + AZD6738
Sensitive: D – Preclinical
olaparib + AZD6738
Sensitive
:
D
IDH1 R132H
Acute Myelogenous Leukemia
IDH1 R132H
Acute Myelogenous Leukemia
venetoclax + midostaurin + LY3410738
Sensitive: D – Preclinical
venetoclax + midostaurin + LY3410738
Sensitive
:
D
venetoclax + midostaurin + LY3410738
Sensitive: D – Preclinical
venetoclax + midostaurin + LY3410738
Sensitive
:
D
IDH1 R132H
Glioma
IDH1 R132H
Glioma
AGI-5198
Sensitive: D – Preclinical
AGI-5198
Sensitive
:
D
AGI-5198
Sensitive: D – Preclinical
AGI-5198
Sensitive
:
D
IDH1 R132H
Acute Myelogenous Leukemia
IDH1 R132H
Acute Myelogenous Leukemia
GSK321
Sensitive: D – Preclinical
GSK321
Sensitive
:
D
GSK321
Sensitive: D – Preclinical
GSK321
Sensitive
:
D
IDH1 R132H
Glioma
IDH1 R132H
Glioma
temozolomide + azacitidine
Sensitive: D – Preclinical
temozolomide + azacitidine
Sensitive
:
D
temozolomide + azacitidine
Sensitive: D – Preclinical
temozolomide + azacitidine
Sensitive
:
D
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