TEST:

Abbott RealTime IDH1

Abbott RealTime IDH1 is an in vitro polymerase chain reaction (PCR) assay for for the qualitative detection of single nucleotide variants (SNVs) coding five IDH1 R132 mutations (R132C, R132H, R132G, R132S, and R132L) in DNA extracted from human blood (EDTA) or bone marrow (EDTA). It is for use with the Abbott m2000rt System. Abbott RealTime IDH1 consists of two kits: Abbott RealTime IDH1 Amplification Reagent Kit and Abbott RealTime IDH1 Control Kit. it is indicated as an aid in identifying acute myeloid leukemia (AML) patients with an isocitrate dehydrogenase-1 (IDH1) mutation for treatment with TIBSOVO® (ivosidenib).