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BIOMARKER:

HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K

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Entrez ID:

Related biomarkers:

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HER-2 positive (332)

HER-2 overexpression (132)

HER-2 negative (120)

HER-2 expression (87)

EGFR expression (46)

HER-2 underexpression (38)

EGFR overexpression (34)

HER-2 negative + PD-L1 expression (12)

EGFR positive (8)

EGFR negative (6)

HR positive + HER-2 negative (5)

EGFR negative + ALK negative (4)

EGFR expression + ALK positive (3)

EGFRVIII expression + PTEN expression (3)

EGFRvIII expression (3)

HER-2 positive + PD-L1 expression (3)

EGFR expression + MET expression (2)

EGFR overexpression + HER-2 overexpression (2)

MMP17 expression + EGFR expression + RB1 expression (2)

MUC1 expression + EGFR expression (2)

TROP2 expression + EGFR expression (2)

CD47 positive + HER-2 positive (2)

CLDN18.2 expression + HER-2 negative (2)

CLDN18.2 positive + HER-2 negative (2)

ER positive + HER-2 negative (2)

FGFR2b overexpression + HER-2 negative (2)

HR positive + HER-2 underexpression (2)

PD-L1 expression + HER-2 overexpression (2)

EGFR expression + HER-2 expression (1)

EGFR underexpression (1)

EGFRVIII overexpression (1)

EPHA2 overexpression + EGFR overexpression (1)

GPC3 positive + EGFR expression (1)

CEACAM6 positive + HER-2 positive (1)

ER negative + HER-2 negative (1)

ER positive + PGR negative + HER-2 negative (1)

HER-2 positive + CAV1 overexpression (1)

HER-2 underexpression + ER underexpression (1)

HR positive + HER-2 positive (1)

MET expression + HER-2 expression (1)

MET overexpression + HER-2 overexpression (1)

TPBG underexpression + HER-2 overexpression (1)

TROP2 expression + HER-2 underexpression (1)

DRD2 expression + EGFR overexpression (0)

YAP1 overexpression + EGFR overexpression (0)

ER negative + HER-2 positive (0)

ER positive + HER-2 positive (0)

ER positive + PGR positive + HER-2 positive (0)

HER-2 amplification + HR-positive (0)

HER-2 negative + AR positive + ER positive (0)

HER-2 negative + CLDN18.2 positive (0)

HER-2 negative + ER positive (0)

HER-2 negative + FGFR2b overexpression (0)

HER-2 negative + HR negative (0)

HER-2 negative + HR negative + PD-L1 expression (0)

HER-2 negative + PGR positive (0)

HER-2 overexpression + HR negative (0)

HER-2 overexpression + HR positive (0)

HER-2 positive + HER-2 overexpression (0)

HER-2 positive + HR negative (0)

HER-2 positive + RAS wild-type (0)

HR negative + HER-2 positive (0)

PD-L1 expression + HER-2 expression (0)

PGR positive + HER-2 positive (0)

HER-2 positive (332)

HER-2 overexpression (132)

HER-2 negative (120)

HER-2 expression (87)

EGFR expression (46)

HER-2 underexpression (38)

EGFR overexpression (34)

HER-2 negative + PD-L1 expression (12)

EGFR positive (8)

EGFR negative (6)

HR positive + HER-2 negative (5)

EGFR negative + ALK negative (4)

EGFR expression + ALK positive (3)

EGFRVIII expression + PTEN expression (3)

EGFRvIII expression (3)

HER-2 positive + PD-L1 expression (3)

EGFR expression + MET expression (2)

EGFR overexpression + HER-2 overexpression (2)

MMP17 expression + EGFR expression + RB1 expression (2)

MUC1 expression + EGFR expression (2)

TROP2 expression + EGFR expression (2)

CD47 positive + HER-2 positive (2)

CLDN18.2 expression + HER-2 negative (2)

CLDN18.2 positive + HER-2 negative (2)

ER positive + HER-2 negative (2)

FGFR2b overexpression + HER-2 negative (2)

HR positive + HER-2 underexpression (2)

PD-L1 expression + HER-2 overexpression (2)

EGFR expression + HER-2 expression (1)

EGFR underexpression (1)

EGFRVIII overexpression (1)

EPHA2 overexpression + EGFR overexpression (1)

GPC3 positive + EGFR expression (1)

CEACAM6 positive + HER-2 positive (1)

ER negative + HER-2 negative (1)

ER positive + PGR negative + HER-2 negative (1)

HER-2 positive + CAV1 overexpression (1)

HER-2 underexpression + ER underexpression (1)

HR positive + HER-2 positive (1)

MET expression + HER-2 expression (1)

MET overexpression + HER-2 overexpression (1)

TPBG underexpression + HER-2 overexpression (1)

TROP2 expression + HER-2 underexpression (1)

DRD2 expression + EGFR overexpression (0)

YAP1 overexpression + EGFR overexpression (0)

ER negative + HER-2 positive (0)

ER positive + HER-2 positive (0)

ER positive + PGR positive + HER-2 positive (0)

HER-2 amplification + HR-positive (0)

HER-2 negative + AR positive + ER positive (0)

HER-2 negative + CLDN18.2 positive (0)

HER-2 negative + ER positive (0)

HER-2 negative + FGFR2b overexpression (0)

HER-2 negative + HR negative (0)

HER-2 negative + HR negative + PD-L1 expression (0)

HER-2 negative + PGR positive (0)

HER-2 overexpression + HR negative (0)

HER-2 overexpression + HR positive (0)

HER-2 positive + HER-2 overexpression (0)

HER-2 positive + HR negative (0)

HER-2 positive + RAS wild-type (0)

HR negative + HER-2 positive (0)

PD-L1 expression + HER-2 expression (0)

PGR positive + HER-2 positive (0)

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HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K	HER2 Positive Breast Cancer	HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K	HER2 Positive Breast Cancer	pyrotinib Sensitive: C4 – Case Studies pyrotinib Sensitive : C4	pyrotinib Sensitive: C4 – Case Studies pyrotinib Sensitive : C4
HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K	Breast Cancer	HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K	Breast Cancer	lapatinib Resistant: C4 – Case Studies lapatinib Resistant : C4	lapatinib Resistant: C4 – Case Studies lapatinib Resistant : C4