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BIOMARKER:

HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K

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Entrez ID:

Related biomarkers:

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HER-2 amplification (129)

EGFR exon 19 deletion (79)

EGFR amplification (52)

EGFR exon 18 deletion (3)

EGFR exon 2-7 deletion + EGFR amplification (2)

EGFR amplification + ERBB2 amplification (1)

EGFR exon 19 deletion + HER-2 amplification (1)

EGFR exon 21 deletion (1)

HER-2 amplification + MET amplification (1)

HER-2 amplification + PTEN deletion (1)

HER-2 exon 19 deletion (1)

MYC amplification + HER-2 amplification (1)

EGFR T790M + exon 19 deletion (0)

EGFR amplifcation (0)

HER-2 amplification + CDK12 amplification (0)

YES1 amplification + HER-2 amplification (0)

HER-2 amplification (129)

EGFR exon 19 deletion (79)

EGFR amplification (52)

EGFR exon 18 deletion (3)

EGFR exon 2-7 deletion + EGFR amplification (2)

EGFR amplification + ERBB2 amplification (1)

EGFR exon 19 deletion + HER-2 amplification (1)

EGFR exon 21 deletion (1)

HER-2 amplification + MET amplification (1)

HER-2 amplification + PTEN deletion (1)

HER-2 exon 19 deletion (1)

MYC amplification + HER-2 amplification (1)

EGFR T790M + exon 19 deletion (0)

EGFR amplifcation (0)

HER-2 amplification + CDK12 amplification (0)

YES1 amplification + HER-2 amplification (0)

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HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K	HER2 Positive Breast Cancer	HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K	HER2 Positive Breast Cancer	pyrotinib Sensitive: C4 – Case Studies pyrotinib Sensitive : C4	pyrotinib Sensitive: C4 – Case Studies pyrotinib Sensitive : C4
HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K	Breast Cancer	HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K	Breast Cancer	lapatinib Resistant: C4 – Case Studies lapatinib Resistant : C4	lapatinib Resistant: C4 – Case Studies lapatinib Resistant : C4