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BIOMARKER:

MMP17 expression + EGFR expression + RB1 expression

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Other names: MMP17, Matrix Metallopeptidase 17, Matrix Metalloproteinase 17 (Membrane-Inserted), Matrix Metallopeptidase 17 (Membrane-Inserted), Membrane-Type Matrix Metalloproteinase 4, Membrane-Type-4 Matrix Metalloproteinase, Matrix Metalloproteinase-17, MT-MMP 4, MT4-MMP, MMP-17 , MT4MMP , MTMMP4, EGFR, ERBB, ERBB1, Epidermal growth factor receptor, RB1, RB Transcriptional Corepressor 1, Protein Phosphatase 1 Regulatory Subunit 130, Prepro-Retinoblastoma-Associated Protein, Retinoblastoma-Associated Protein, Retinoblastoma 1, P110-RB1, P105-Rb, Pp110, PRb, Exon 17 Tumor GOS561 Substitution Mutation Causes Premature Stop, GOS563 Exon 17 Substitution Mutation Causes Premature Stop, Retinoblastoma Suspectibility Protein, Osteosarcoma, PPP1R130, OSRC, RB, Rb, pRb
Entrez ID:
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Trials
MMP17 expression + EGFR expression + RB1 expression
Triple Negative Breast Cancer
erlotinib + palbociclib
Sensitive: C3 – Early Trials
MMP17 expression + EGFR expression + RB1 expression
Triple Negative Breast Cancer
erlotinib
Resistant: C3 – Early Trials