^
    BIOMARKER:

    HER-2 underexpression

    i
    Other names: ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
    Entrez ID:
    2064
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    HER-2 underexpression
    Gastroesophageal Junction Adenocarcinoma
    fam-trastuzumab deruxtecan-nxki
    Sensitive: C2 – Inclusion Criteria
    HER-2 underexpression
    Breast Cancer
    fam-trastuzumab deruxtecan-nxki
    Sensitive: C2 – Inclusion Criteria
    HER-2 underexpression
    HER2 Positive Breast Cancer
    fam-trastuzumab deruxtecan-nxki
    Sensitive: C2 – Inclusion Criteria
    HER-2 underexpression
    Gastric Cancer
    fam-trastuzumab deruxtecan-nxki
    Sensitive: C2 – Inclusion Criteria
    HER-2 underexpression
    Solid Tumor
    KN046 + KN026
    Sensitive: C3 – Early Trials
    HER-2 underexpression
    LUAD
    ado-trastuzumab emtansine
    Sensitive: C3 – Early Trials
    HER-2 underexpression
    HER2 Positive Breast Cancer
    SYD985
    Sensitive: C3 – Early Trials
    HER-2 underexpression
    Hormone Receptor Positive Breast Cancer
    SYD985
    Sensitive: C3 – Early Trials
    HER-2 underexpression
    Ovarian Cancer
    olaparib + niraparib + SYD985
    Sensitive: D – Preclinical
    HER-2 underexpression
    CRC
    AMX-818
    Sensitive: D – Preclinical
    HER-2 underexpression
    Breast Cancer
    SAR443216
    Sensitive: D – Preclinical