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BIOMARKER:
GNA11 mutation
i
Other names:
G Protein Subunit Alpha 11, Guanine Nucleotide Binding Protein (G Protein) Alpha 11 (Gq Class), Guanine Nucleotide-Binding Protein G(Y) Subunit Alpha, Guanine Nucleotide-Binding Protein Subunit Alpha-11, G Alpha-11, Hypocalciuric Hypercalcemia 2, G-Protein Subunit Alpha-11, GNA-11, HYPOC2, FBH2, FHH2, HHC2, GA11, FBH
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Entrez ID:
2767
Related biomarkers:
Mutation
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VERI cancer hierarchy
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GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
selumetinib
Sensitive: C2 – Inclusion Criteria
selumetinib
Sensitive
:
C2
selumetinib
Sensitive: C2 – Inclusion Criteria
selumetinib
Sensitive
:
C2
GNA11 mutation
Melanoma
GNA11 mutation
Melanoma
vorinostat
Sensitive: C2 – Inclusion Criteria
vorinostat
Sensitive
:
C2
vorinostat
Sensitive: C2 – Inclusion Criteria
vorinostat
Sensitive
:
C2
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
pembrolizumab
Sensitive: C3 – Early Trials
pembrolizumab
Sensitive
:
C3
pembrolizumab
Sensitive: C3 – Early Trials
pembrolizumab
Sensitive
:
C3
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
AEB071
Sensitive: C3 – Early Trials
AEB071
Sensitive
:
C3
AEB071
Sensitive: C3 – Early Trials
AEB071
Sensitive
:
C3
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
cabozantinib capsule
Sensitive: C3 – Early Trials
cabozantinib capsule
Sensitive
:
C3
cabozantinib capsule
Sensitive: C3 – Early Trials
cabozantinib capsule
Sensitive
:
C3
GNA11 mutation
Non Small Cell Lung Cancer
GNA11 mutation
Non Small Cell Lung Cancer
nivolumab
Resistant: C3 – Early Trials
nivolumab
Resistant
:
C3
nivolumab
Resistant: C3 – Early Trials
nivolumab
Resistant
:
C3
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
AEB071 + AHT956
Sensitive: D – Preclinical
AEB071 + AHT956
Sensitive
:
D
AEB071 + AHT956
Sensitive: D – Preclinical
AEB071 + AHT956
Sensitive
:
D
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
FR900359
Sensitive: D – Preclinical
FR900359
Sensitive
:
D
FR900359
Sensitive: D – Preclinical
FR900359
Sensitive
:
D
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
binimetinib + AEB071
Sensitive: D – Preclinical
binimetinib + AEB071
Sensitive
:
D
binimetinib + AEB071
Sensitive: D – Preclinical
binimetinib + AEB071
Sensitive
:
D
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
verteporfin
Sensitive: D – Preclinical
verteporfin
Sensitive
:
D
verteporfin
Sensitive: D – Preclinical
verteporfin
Sensitive
:
D
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
AEB071 + CGM097
Sensitive: D – Preclinical
AEB071 + CGM097
Sensitive
:
D
AEB071 + CGM097
Sensitive: D – Preclinical
AEB071 + CGM097
Sensitive
:
D
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
everolimus + AEB071
Sensitive: D – Preclinical
everolimus + AEB071
Sensitive
:
D
everolimus + AEB071
Sensitive: D – Preclinical
everolimus + AEB071
Sensitive
:
D
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