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BIOMARKER:

GNA11 mutation

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Other names: G Protein Subunit Alpha 11, Guanine Nucleotide Binding Protein (G Protein) Alpha 11 (Gq Class), Guanine Nucleotide-Binding Protein G(Y) Subunit Alpha, Guanine Nucleotide-Binding Protein Subunit Alpha-11, G Alpha-11, Hypocalciuric Hypercalcemia 2, G-Protein Subunit Alpha-11, GNA-11, HYPOC2, FBH2, FHH2, HHC2, GA11, FBH
Entrez ID:
Related biomarkers:
GNA11 mutation
Uveal Melanoma
selumetinib
Sensitive: C2 – Inclusion Criteria
GNA11 mutation
Melanoma
vorinostat
Sensitive: C2 – Inclusion Criteria
GNA11 mutation
Uveal Melanoma
pembrolizumab
Sensitive: C3 – Early Trials
GNA11 mutation
Uveal Melanoma
AEB071
Sensitive: C3 – Early Trials
GNA11 mutation
Uveal Melanoma
cabozantinib capsule
Sensitive: C3 – Early Trials
GNA11 mutation
NSCLC
nivolumab
Resistant: C3 – Early Trials
GNA11 mutation
Uveal Melanoma
AEB071 + AHT956
Sensitive: D – Preclinical
GNA11 mutation
Uveal Melanoma
FR900359
Sensitive: D – Preclinical
GNA11 mutation
Uveal Melanoma
binimetinib + AEB071
Sensitive: D – Preclinical
GNA11 mutation
Uveal Melanoma
verteporfin
Sensitive: D – Preclinical
GNA11 mutation
Uveal Melanoma
AEB071 + CGM097
Sensitive: D – Preclinical
GNA11 mutation
Uveal Melanoma
everolimus + AEB071
Sensitive: D – Preclinical
GNA11 mutation
Uveal Melanoma
JQ-1
Sensitive: D – Preclinical
GNA11 mutation
Uveal Melanoma
PD-0325901 + AEB071
Sensitive: D – Preclinical