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BIOMARKER:
GNA11 mutation
i
Other names:
G Protein Subunit Alpha 11, Guanine Nucleotide Binding Protein (G Protein) Alpha 11 (Gq Class), Guanine Nucleotide-Binding Protein G(Y) Subunit Alpha, Guanine Nucleotide-Binding Protein Subunit Alpha-11, G Alpha-11, Hypocalciuric Hypercalcemia 2, G-Protein Subunit Alpha-11, GNA-11, HYPOC2, FBH2, FHH2, HHC2, GA11, FBH
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Entrez ID:
2767
Related biomarkers:
Mutation
‹
›
Associations
(16)
News
Trials
Phase
Status
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Phase
Status
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Testing Trametinib as a Potential Targeted Treatment in Cancers With GNAQ or GNA11 Genetic Changes (MATCH-Subprotocol S2) (NCT04439357)
Phase 2
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 2
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
02/13/2024
Initiation :
02/25/2016
Primary completion :
09/01/2020
Completion :
12/31/2025
GNAQ • GNA11
|
GNAQ mutation • GNA11 mutation
|
Mekinist (trametinib)
The Role of Genetic Mutations and of Circulating mRNAs in Uveal Melanoma (NCT05179174)
Phase N/A
University of Catania
University of Catania
Recruiting
Phase N/A
University of Catania
Recruiting
Last update posted :
01/05/2022
Initiation :
04/20/2021
Primary completion :
04/01/2023
Completion :
12/01/2023
GNA11
|
GNA11 mutation
Efficacy and Safety Study of GSK1120212, a MEK Inhibitor, in Subjects With Uveal Melanoma (NCT01328106)
Phase 2
GlaxoSmithKline
GlaxoSmithKline
Withdrawn
Phase 2
GlaxoSmithKline
Withdrawn
Last update posted :
12/12/2017
Initiation :
11/01/2010
Primary completion :
08/01/2011
Completion :
05/01/2012
GNAQ • GNA11
|
GNAQ mutation • GNA11 mutation
|
Mekinist (trametinib)
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