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BIOMARKER:
EGFR wild-type + ALK wild-type
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor, NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
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Entrez ID:
1956
;
238
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ALK positive (74)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
ALK expression + PDGFRA expression (1)
ALK expression + PDGFRB expression (1)
ALK overexpression (1)
ALK positive + ROS1 positive (1)
ALK positive + YAP1 overexpression (1)
ALK positive + YES1 overexpression (1)
KRT7 positive + NKX2-1 positive + ALK overexpression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
ALK positive (74)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
ALK expression + PDGFRA expression (1)
ALK expression + PDGFRB expression (1)
ALK overexpression (1)
ALK positive + ROS1 positive (1)
ALK positive + YAP1 overexpression (1)
ALK positive + YES1 overexpression (1)
KRT7 positive + NKX2-1 positive + ALK overexpression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
›
Associations
News
Trials
VERI cancer hierarchy
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EGFR wild-type + ALK wild-type
Lung Non-Squamous Non-Small Cell Cancer
EGFR wild-type + ALK wild-type
Lung Non-Squamous Non-Small Cell Cancer
serplulimab
Sensitive: A1 - Approval
Henlius Press Release - 2 weeks (New A1)
serplulimab
Sensitive
:
A1
Henlius Press Release - 2wk
serplulimab
Sensitive: A1 - Approval
Henlius Press Release - 2 weeks
serplulimab
Sensitive
:
A1
Henlius Press Release - 2 weeks - (New A1)
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
rivoceranib
Sensitive: C2 – Inclusion Criteria
rivoceranib
Sensitive
:
C2
rivoceranib
Sensitive: C2 – Inclusion Criteria
rivoceranib
Sensitive
:
C2
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
SI-B001
Sensitive: C2 – Inclusion Criteria
SI-B001
Sensitive
:
C2
SI-B001
Sensitive: C2 – Inclusion Criteria
SI-B001
Sensitive
:
C2
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
pembrolizumab
Sensitive: C2 – Inclusion Criteria
pembrolizumab
Sensitive
:
C2
pembrolizumab
Sensitive: C2 – Inclusion Criteria
pembrolizumab
Sensitive
:
C2
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
toripalimab-tpzi
Sensitive: C3 – Early Trials
toripalimab-tpzi
Sensitive
:
C3
toripalimab-tpzi
Sensitive: C3 – Early Trials
toripalimab-tpzi
Sensitive
:
C3
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
EGFR wild-type + ALK wild-type
Non Small Cell Lung Cancer
anlotinib
Sensitive: C3 – Early Trials
anlotinib
Sensitive
:
C3
anlotinib
Sensitive: C3 – Early Trials
anlotinib
Sensitive
:
C3
EGFR wild-type + ALK wild-type
Lung Adenocarcinoma
EGFR wild-type + ALK wild-type
Lung Adenocarcinoma
rivoceranib
Sensitive: C4 – Case Studies
rivoceranib
Sensitive
:
C4
rivoceranib
Sensitive: C4 – Case Studies
rivoceranib
Sensitive
:
C4
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