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BIOMARKER:
EGFR exon 19 deletion
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
›
Related tests:
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (21)
cobas® EGFR Mutation Test v2 (13)
Oncomine™ Dx Target Test (10)
therascreen® EGFR RGQ PCR Kit (5)
MI Cancer Seek™
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (21)
cobas® EGFR Mutation Test v2 (13)
Oncomine™ Dx Target Test (10)
therascreen® EGFR RGQ PCR Kit (5)
MI Cancer Seek™
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
afatinib
Sensitive: A1 - Approval
afatinib
Sensitive
:
A1
afatinib
Sensitive: A1 - Approval
afatinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
gefitinib
Sensitive: A1 - Approval
gefitinib
Sensitive
:
A1
gefitinib
Sensitive: A1 - Approval
gefitinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
dacomitinib
Sensitive: A1 - Approval
dacomitinib
Sensitive
:
A1
dacomitinib
Sensitive: A1 - Approval
dacomitinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
erlotinib
Sensitive: A1 - Approval
erlotinib
Sensitive
:
A1
erlotinib
Sensitive: A1 - Approval
erlotinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
erlotinib + ramucirumab
Sensitive: A1 - Approval
erlotinib + ramucirumab
Sensitive
:
A1
erlotinib + ramucirumab
Sensitive: A1 - Approval
erlotinib + ramucirumab
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
bevacizumab + erlotinib
Sensitive: A2 - Guideline
bevacizumab + erlotinib
Sensitive
:
A2
bevacizumab + erlotinib
Sensitive: A2 - Guideline
bevacizumab + erlotinib
Sensitive
:
A2
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR exon 19 deletion
Lung Adenocarcinoma
EGFR exon 19 deletion
Lung Adenocarcinoma
gefitinib
Sensitive: B - Late Trials
gefitinib
Sensitive
:
B
gefitinib
Sensitive: B - Late Trials
gefitinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
icotinib
Sensitive: B - Late Trials
icotinib
Sensitive
:
B
icotinib
Sensitive: B - Late Trials
icotinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
gefitinib + rivoceranib
Sensitive: B - Late Trials
gefitinib + rivoceranib
Sensitive
:
B
gefitinib + rivoceranib
Sensitive: B - Late Trials
gefitinib + rivoceranib
Sensitive
:
B
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
bevacizumab + atezolizumab
Sensitive: B - Late Trials
bevacizumab + atezolizumab
Sensitive
:
B
bevacizumab + atezolizumab
Sensitive: B - Late Trials
bevacizumab + atezolizumab
Sensitive
:
B
EGFR exon 19 deletion
Lung Adenocarcinoma
EGFR exon 19 deletion
Lung Adenocarcinoma
afatinib
Sensitive: B - Late Trials
afatinib
Sensitive
:
B
afatinib
Sensitive: B - Late Trials
afatinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
gefitinib + ramucirumab
Sensitive: B - Late Trials
gefitinib + ramucirumab
Sensitive
:
B
gefitinib + ramucirumab
Sensitive: B - Late Trials
gefitinib + ramucirumab
Sensitive
:
B
EGFR exon 19 deletion
Lung Non-Small Cell Squamous Cancer
EGFR exon 19 deletion
Lung Non-Small Cell Squamous Cancer
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR inhibitor
Sensitive: B - Late Trials
EGFR inhibitor
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
aumolertinib
Sensitive: B - Late Trials
aumolertinib
Sensitive
:
B
aumolertinib
Sensitive: B - Late Trials
aumolertinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
firmonertinib
Sensitive: B - Late Trials
firmonertinib
Sensitive
:
B
firmonertinib
Sensitive: B - Late Trials
firmonertinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
lazertinib
Sensitive: B - Late Trials
lazertinib
Sensitive
:
B
lazertinib
Sensitive: B - Late Trials
lazertinib
Sensitive
:
B
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
befotertinib
Sensitive: B - Late Trials
befotertinib
Sensitive
:
B
befotertinib
Sensitive: B - Late Trials
befotertinib
Sensitive
:
B
EGFR exon 19 deletion
Lung Adenocarcinoma
EGFR exon 19 deletion
Lung Adenocarcinoma
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
EGFR exon 19 deletion
Small Cell Lung Cancer
EGFR exon 19 deletion
Small Cell Lung Cancer
gefitinib
Sensitive: C1 - Off-label
gefitinib
Sensitive
:
C1
gefitinib
Sensitive: C1 - Off-label
gefitinib
Sensitive
:
C1
EGFR exon 19 deletion
Lung Cancer
EGFR exon 19 deletion
Lung Cancer
gefitinib
Sensitive: C1 - Off-label
gefitinib
Sensitive
:
C1
gefitinib
Sensitive: C1 - Off-label
gefitinib
Sensitive
:
C1
EGFR exon 19 deletion
Small Cell Lung Cancer
EGFR exon 19 deletion
Small Cell Lung Cancer
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
osimertinib + gefitinib
Sensitive: C2 – Inclusion Criteria
osimertinib + gefitinib
Sensitive
:
C2
osimertinib + gefitinib
Sensitive: C2 – Inclusion Criteria
osimertinib + gefitinib
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
anlotinib + icotinib
Sensitive: C2 – Inclusion Criteria
anlotinib + icotinib
Sensitive
:
C2
anlotinib + icotinib
Sensitive: C2 – Inclusion Criteria
anlotinib + icotinib
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGF816
Sensitive: C2 – Inclusion Criteria
EGF816
Sensitive
:
C2
EGF816
Sensitive: C2 – Inclusion Criteria
EGF816
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
U3-1402
Sensitive: C2 – Inclusion Criteria
U3-1402
Sensitive
:
C2
U3-1402
Sensitive: C2 – Inclusion Criteria
U3-1402
Sensitive
:
C2
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
bevacizumab + osimertinib
Sensitive: C2 – Inclusion Criteria
bevacizumab + osimertinib
Sensitive
:
C2
bevacizumab + osimertinib
Sensitive: C2 – Inclusion Criteria
bevacizumab + osimertinib
Sensitive
:
C2
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