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BIOMARKER:

MYC rearrangement + BCL2 rearrangement

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Other names: MYC, bHLHe39, c-Myc, MYCC, V-myc avian myelocytomatosis viral oncogene homolog, BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2
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Entrez ID:
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
lisocabtagene maraleucel
Sensitive
:
A2
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
lenalidomide
Sensitive
:
B
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
cytarabine + methotrexate
Resistant
:
C3
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
rituximab
Resistant
:
C3
MYC rearrangement + BCL2 rearrangement
Lymphoma
lisocabtagene maraleucel
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement
Non-Hodgkin’s Lymphoma
ibrutinib
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement
Follicular Lymphoma
EPOCH-R
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement
Follicular Lymphoma
R-DHAP
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
lenalidomide + zanubrutinib
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
loncastuximab tesirine
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
C-RICE
Sensitive
:
C3
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
IACS-010759
Sensitive
:
D
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
ibrutinib
Resistant
:
D
MYC rearrangement + BCL2 rearrangement
Non-Hodgkin’s Lymphoma
ibrutinib + alemtuzumab
Sensitive
:
D
MYC rearrangement + BCL2 rearrangement
Lymphoma
HZX-02-059
Sensitive
:
D
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
venetoclax
Sensitive
:
D
MYC rearrangement + BCL2 rearrangement
Diffuse Large B Cell Lymphoma
copanlisib
Sensitive
:
D
MYC rearrangement + BCL2 rearrangement
Lymphoma
venetoclax + DUP 785
Sensitive
:
D