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BIOMARKER:

MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement

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Other names: MYC, bHLHe39, c-Myc, MYCC, V-myc avian myelocytomatosis viral oncogene homolog, BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2, BCL6, BCL5, BCL6A, LAZ3, ZBTB27, ZNF51, B-cell CLL/lymphoma 6
Entrez ID:
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Trials
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
lisocabtagene maraleucel
Sensitive: A2 - Guideline
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement
Lymphoma
lisocabtagene maraleucel
Sensitive: C2 – Inclusion Criteria
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
loncastuximab tesirine
Sensitive: C3 – Early Trials