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BIOMARKER:
EGFR H1975
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
›
Associations
(2)
News
Trials
Search handles
@StephenVLiu
Search handles
@StephenVLiu
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Latest
over3years
First, #VEGF is highly expressed in #EGFR mutant cell lines (HCC827, H3255) and TKI therapy drops VEGF mRNA while in resistant setting (H1975 with T790M), erlotinib has no impact on high VEGF levels. In EGFRmt NSCLC, VEGF secretion is EGFR dependent. (@StephenVLiu)
over 3 years ago
Preclinical
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR T790M • EGFR expression • EGFR overexpression • EGFR H1975
|
erlotinib
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