Idylla™ MSI Test performs the detection of microsatellite instability directly from formalin-fixed paraffin embedded (FFPE) human cancer tissue sections utilizing a PCR reaction followed by high-resolution melting curve analysis. Test performs detection of mutations in 7 novel MSI loci (ACVR2A, BTBD7, DIDO1, MRE11, RYR3, SEC31A, and SULF2).
Colorectal Cancer
ACVR2A (Activin A Receptor Type 2A), BTBD7 (BTB Domain Containing 7), MRE11A (MRE11 homolog, double strand break repair nuclease), MSI (Microsatellite instability), RYR3 (Ryanodine Receptor 3), SEC31A (SEC31 Homolog A COPII Coat Complex Component)
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