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The Idylla™ IDH1-2 Mutation Assay Kit (RUO) is the first test developed using the Idylla™ FLEX technology. Mutations in the isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) genes are oncogenic drivers that are frequently found in a variety of human malignancies, including gliomas, acute myeloid leukemia, cholangiocarcinoma, chondrosarcoma and thyroid carcinoma. The Idylla™ IDH1-2 Mutation Assay Kit (RUO) can detect 5 mutations in IDH1 and 10 mutations in IDH2, along with an integrated processing control. The turn-around-time is less than 2 hours from sample to result.
Cancer:
Acute Myelogenous Leukemia, Cholangiocarcinoma, Glioma, Thyroid Gland Carcinoma
Gene:
IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2)