TEST:

AmoyDx® BRAF V600 Mutations Detection Kit

"ctDNA is a feasible source of genetic material for BRAF mutations assessment in patients with advanced melanoma in clinical practice, especially when a tissue sample is not available or in patients with rapidly progressive disease. The median TAT for ctDNA testing is significantly shorter than for tissue samples, while sensitivity and specificity are>80% highlighting the clinical utility of liquid biopsy. Treatment with BRAF/MEKi based on the results of liquid biopsy gives comparable outcomes to those reported in the literature for the general population."