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CANCER:

Myelodysplastic Syndrome

IDH1 mutation
Myelodysplastic Syndrome
venetoclax + ivosidenib
Sensitive
:
C3
SOHO 2022 - 1 week - (New C3)
TP53 mutation
Myelodysplastic Syndrome
GS-4721
Sensitive
:
C3
SOHO 2022 - 1 week - (New C3)
TP53 wild-type
Myelodysplastic Syndrome
GS-4721
Sensitive
:
C3
SOHO 2022 - 1 week - (New C3)
No biomarker
Myelodysplastic Syndrome
decitabine / cedazuridine
Sensitive
:
A1
No biomarker
Myelodysplastic Syndrome
luspatercept-aamt
Sensitive
:
A1
Chr del(5q)
Myelodysplastic Syndrome
lenalidomide
Sensitive
:
A1
No biomarker
Myelodysplastic Syndrome
azacitidine
Sensitive
:
A1
No biomarker
Myelodysplastic Syndrome
decitabine
Sensitive
:
A1
PDGFRA rearrangement
Myelodysplastic Syndrome
imatinib
Sensitive
:
A1
CALR mutation
Myelodysplastic Syndrome
luspatercept-aamt
Sensitive
:
A2
CALR mutation
Myelodysplastic Syndrome
lenalidomide
Sensitive
:
A2
MPL W515L
Myelodysplastic Syndrome
luspatercept-aamt
Sensitive
:
A2
MPL W515L
Myelodysplastic Syndrome
lenalidomide
Sensitive
:
A2
JAK2 V617F
Myelodysplastic Syndrome
luspatercept-aamt
Sensitive
:
A2
SF3B1 mutation
Myelodysplastic Syndrome
luspatercept-aamt
Sensitive
:
A2
JAK2 V617F
Myelodysplastic Syndrome
lenalidomide
Sensitive
:
A2
RUNX1 mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive
:
A2
SETBP1 mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive
:
A2
CBL mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive
:
A2
NRAS mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive
:
A2
ASXL1 mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive
:
A2
SRSF2 mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive
:
A2
TET2 mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive
:
A2
ETNK1 mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive
:
A2
STAT3 mutation
Myelodysplastic Syndrome
eltrombopag + cyclosporin A microemulsion
Sensitive
:
A2
No biomarker
Myelodysplastic Syndrome
eltrombopag + cyclosporin A microemulsion
Sensitive
:
A2
TP53 mutation
Myelodysplastic Syndrome
APR-246
Sensitive
:
B
No biomarker
Myelodysplastic Syndrome
GS-4721
Sensitive
:
B
DNMT3A mutation + SF3B1 mutation
Myelodysplastic Syndrome
lenalidomide
Resistant
:
B
No biomarker
Myelodysplastic Syndrome
MLN4924
Sensitive
:
B
No biomarker
Myelodysplastic Syndrome
lenalidomide
Sensitive
:
B
Chr del(5)(q31)
Myelodysplastic Syndrome
lenalidomide
Sensitive
:
B
No biomarker
Myelodysplastic Syndrome
MBG453
Sensitive
:
B
No biomarker
Myelodysplastic Syndrome
venetoclax
Sensitive
:
B
No biomarker
Myelodysplastic Syndrome
KPT-8602
Sensitive
:
B