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CANCER:

Myelodysplastic Syndrome

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No biomarker	Myelodysplastic Syndrome	No biomarker	Myelodysplastic Syndrome	decitabine/cedazuridine Sensitive: A1 - Approval decitabine / cedazuridine Sensitive : A1	decitabine/cedazuridine Sensitive: A1 - Approval decitabine / cedazuridine Sensitive : A1
No biomarker	Myelodysplastic Syndrome	No biomarker	Myelodysplastic Syndrome	luspatercept-aamt Sensitive: A1 - Approval luspatercept-aamt Sensitive : A1	luspatercept-aamt Sensitive: A1 - Approval luspatercept-aamt Sensitive : A1
Chr del(5q)	Myelodysplastic Syndrome	Chr del(5q)	Myelodysplastic Syndrome	lenalidomide Sensitive: A1 - Approval lenalidomide Sensitive : A1	lenalidomide Sensitive: A1 - Approval lenalidomide Sensitive : A1
No biomarker	Myelodysplastic Syndrome	No biomarker	Myelodysplastic Syndrome	azacitidine Sensitive: A1 - Approval azacitidine Sensitive : A1	azacitidine Sensitive: A1 - Approval azacitidine Sensitive : A1
No biomarker	Myelodysplastic Syndrome	No biomarker	Myelodysplastic Syndrome	decitabine Sensitive: A1 - Approval decitabine Sensitive : A1	decitabine Sensitive: A1 - Approval decitabine Sensitive : A1
PDGFRA rearrangement	Myelodysplastic Syndrome	PDGFRA rearrangement	Myelodysplastic Syndrome	imatinib Sensitive: A1 - Approval imatinib Sensitive : A1	imatinib Sensitive: A1 - Approval imatinib Sensitive : A1
IDH1 mutation	Myelodysplastic Syndrome	IDH1 mutation	Myelodysplastic Syndrome	ivosidenib Sensitive: A1 - Approval ivosidenib Sensitive : A1	ivosidenib Sensitive: A1 - Approval ivosidenib Sensitive : A1
CALR mutation	Myelodysplastic Syndrome	CALR mutation	Myelodysplastic Syndrome	luspatercept-aamt Sensitive: A2 - Guideline luspatercept-aamt Sensitive : A2	luspatercept-aamt Sensitive: A2 - Guideline luspatercept-aamt Sensitive : A2
CALR mutation	Myelodysplastic Syndrome	CALR mutation	Myelodysplastic Syndrome	lenalidomide Sensitive: A2 - Guideline lenalidomide Sensitive : A2	lenalidomide Sensitive: A2 - Guideline lenalidomide Sensitive : A2
SF3B1 mutation	Myelodysplastic Syndrome	SF3B1 mutation	Myelodysplastic Syndrome	luspatercept-aamt Sensitive: A2 - Guideline luspatercept-aamt Sensitive : A2	luspatercept-aamt Sensitive: A2 - Guideline luspatercept-aamt Sensitive : A2
RUNX1 mutation	Myelodysplastic Syndrome	RUNX1 mutation	Myelodysplastic Syndrome	ruxolitinib Sensitive: A2 - Guideline ruxolitinib Sensitive : A2	ruxolitinib Sensitive: A2 - Guideline ruxolitinib Sensitive : A2
SETBP1 mutation	Myelodysplastic Syndrome	SETBP1 mutation	Myelodysplastic Syndrome	ruxolitinib Sensitive: A2 - Guideline ruxolitinib Sensitive : A2	ruxolitinib Sensitive: A2 - Guideline ruxolitinib Sensitive : A2