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The Vysis CLL FISH Probe Kit uses FISH DNA probe technology to determine deletion status of probe targets for locus-specific identifier (LSI) TP53 (containing tumor protein p53 gene, located on chromosome 17p), LSI ATM (containing ataxia telangiectasia mutated gene, located on chromosome 11q), and LSI D13S319 (containing marker D13S319, located on chromosome 13q), as well as determining trisomy 12 with CEP12 (D12Z3 alpha satellite, located on chromosome 12). The Vysis CLL FISH Probe Kit includes LSI 13q34 (containing lysosomal-associated membrane protein 1 gene, located on chromosome 13q) as a control probe.
Cancer:
Chronic Lymphocytic Leukemia
Gene:
ATM (ATM serine/threonine kinase), TP53 (Tumor protein P53)
Drug:
Venclexta (venetoclax)
Method:
Fluorescence in situ hybridization (FISH)
Approvals
Date
Cancer
Gene
Drug
By
Confirmatory trial(s)