IO biomarker
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KRAS (KRAS proto-oncogene GTPase) • BRAF (B-raf proto-oncogene) • TP53 (Tumor protein P53) • NRAS (Neuroblastoma RAS viral oncogene homolog) • BCL2L1 (BCL2-like 1)
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TP53 mutation • KRAS mutation • BRAF mutation • NRAS mutation • BRAF V600 • Chr t(11;14) • BCL2L1 overexpression • MCL1 overexpression • BCL2 expression • MCL1 expression • IGH translocation
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Venclexta (venetoclax) • sabutoclax (ONT-701)