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DRUG:

PF-06671008

i
Other names: PF-06671008, PF-6671008, PF 6671008
Associations
Trials
Company:
Pfizer
Drug class:
CD3 agonist, CDH3 inhibitor
Related drugs:
Associations
Trials
over2years
A Phase 1 Dose-Escalation Study of PF-06671008, a Bispecific T-Cell-Engaging Therapy Targeting P-Cadherin in Patients With Advanced Solid Tumors. (PubMed, Front Immunol)
Cytokine peak concentrations and CRS grade appeared to positively correlate with C. Although the study was terminated due to limited antitumor activity, it provides important insights into understanding and managing immune-related adverse events resulting from this class of molecules. URL: https://clinicaltrials.gov/ct2/show/NCT02659631, ClinicalTrials.gov Identifier: NCT02659631.
P1 data • Clinical Trial,Phase I • Journal
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CDH3 (Cadherin 3)
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PF-06671008