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DRUG:
JNJ-8343
i
Other names:
JNJ-8343, JNJ-78278343, JNJ78278343, JNJ8343, JNJ 78278343, JNJ 8343
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to learn more about our Premium Content:
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Associations
News
Trials
Company:
J&J, Zymeworks
Drug class:
CD3 agonist, KLK2 inhibitor
Related drugs:
‹
blinatumomab (52)
epcoritamab-bysp (11)
elranatamab-bcmm (8)
tebentafusp-tebn (7)
MGD006 (6)
BI 764532 (5)
tarlatamab-dlle (4)
SAR442257 (4)
AZD5863 (3)
CTIM-76 (3)
EX103 (3)
JNJ-5322 (3)
A-319 (2)
AMG 794 (2)
ASP2138 (2)
mosunetuzumab-axgb (2)
NVG-111 (2)
talquetamab-tgvs (2)
teclistamab-cqyv (2)
VIR-5818 (2)
CC-93269 (2)
IMC-F106C (2)
IGM-2323 (2)
AMV564 (2)
CLN-978 (1)
CT-95 (1)
glofitamab-gxbm (1)
GEN1047 (1)
ISB 1342 (1)
MGD024 (1)
odronextamab (1)
SAR443216 (1)
GNC-035 (1)
AMG 701 (1)
MK-4002 (1)
REGN4018 (1)
XmAb14045 (1)
JNJ-63898081 (1)
AMG 509 (1)
A-337 (0)
ABBV-184 (0)
ABBV-383 IV (0)
ADG138 (0)
AFM11 (0)
AMG 211 (0)
AMG 305 (0)
AMG 562 (0)
ASP2074 (0)
AVC-001 (0)
AZD0486 (0)
BA1202 (0)
BC3448 (0)
BI 765049 (0)
BNT142 (0)
BS006 (0)
CBA-1535 (0)
CC-1 (0)
CC-3 (0)
CCW702 (0)
CD30 biAb-AATC (0)
CLN-049 (0)
CM350 (0)
CM355 (0)
CMG1A46 (0)
ERY974 (0)
TRBS07 (0)
F182112 (0)
GB261 (0)
GEM333 (0)
GEN1044 (0)
GEN3017 (0)
GNC-039 (0)
GNR-084 (0)
HBM7004 (0)
HPN536 (0)
IBI-389 (0)
IGM-2537 (0)
IGM-2644 (0)
IO-312 (0)
ISB 1302 (0)
ISB 2001 (0)
JNJ-6358 (0)
JNJ-63709178 (0)
JNJ-67571244 (0)
JNJ-8543 (0)
JNJ-8902 (0)
JS203 (0)
LBL-033 (0)
FBTA05 (0)
M701 (0)
M802 (0)
MBS314 (0)
MK-6070 (0)
MP0533 (0)
NG-641 (0)
NGM936 (0)
NILK-2301 (0)
NILK-2501 (0)
NM28-2746 (0)
PF-06671008 (0)
PF-07062119 (0)
PF-07260437 (0)
PIT565 (0)
QLS31904 (0)
QLS31905 (0)
QLS32015 (0)
RG6007 (0)
RG6129 (0)
RG6232 (0)
RG6286 (0)
RG6353 (0)
RG6524 (0)
RGV004 (0)
catumaxomab (0)
SAIL66 (0)
SAR440234 (0)
TAK-186 (0)
TQB2825 (0)
TQB2934 (0)
UMG2-CD3 BTCE (0)
Undisclosed HER2Bi-armed ATC (0)
WVT078 (0)
XmAb968 (0)
Y150 (0)
ZG006 (0)
AMG 160 (0)
activated CIK and bispecific antibody (0)
activated CIK-anti-CD3/MUC1/CEA/EpCAM/GPC3 antibody (0)
ARB202 (0)
RG6160 (0)
RG7802 (0)
AMG 330 (0)
AMG 673 (0)
GNC-038 (0)
AMG 596 (0)
RG6234 (0)
AMG 910 (0)
huCD33-BsAb (0)
REGN5458 (0)
APVO436 (0)
GD2xCD3 (0)
MGD009 (0)
AMG 420 (0)
XmAb13676 (0)
JNJ-8780 (0)
RG6194 (0)
AMG 110 (0)
MCLA-117 (0)
XmAb18087 (0)
AMG 199 (0)
REGN5459 (0)
JNJ-6420 (0)
blinatumomab (52)
epcoritamab-bysp (11)
elranatamab-bcmm (8)
tebentafusp-tebn (7)
MGD006 (6)
BI 764532 (5)
tarlatamab-dlle (4)
SAR442257 (4)
AZD5863 (3)
CTIM-76 (3)
EX103 (3)
JNJ-5322 (3)
A-319 (2)
AMG 794 (2)
ASP2138 (2)
mosunetuzumab-axgb (2)
NVG-111 (2)
talquetamab-tgvs (2)
teclistamab-cqyv (2)
VIR-5818 (2)
CC-93269 (2)
IMC-F106C (2)
IGM-2323 (2)
AMV564 (2)
CLN-978 (1)
CT-95 (1)
glofitamab-gxbm (1)
GEN1047 (1)
ISB 1342 (1)
MGD024 (1)
odronextamab (1)
SAR443216 (1)
GNC-035 (1)
AMG 701 (1)
MK-4002 (1)
REGN4018 (1)
XmAb14045 (1)
JNJ-63898081 (1)
AMG 509 (1)
A-337 (0)
ABBV-184 (0)
ABBV-383 IV (0)
ADG138 (0)
AFM11 (0)
AMG 211 (0)
AMG 305 (0)
AMG 562 (0)
ASP2074 (0)
AVC-001 (0)
AZD0486 (0)
BA1202 (0)
BC3448 (0)
BI 765049 (0)
BNT142 (0)
BS006 (0)
CBA-1535 (0)
CC-1 (0)
CC-3 (0)
CCW702 (0)
CD30 biAb-AATC (0)
CLN-049 (0)
CM350 (0)
CM355 (0)
CMG1A46 (0)
ERY974 (0)
TRBS07 (0)
F182112 (0)
GB261 (0)
GEM333 (0)
GEN1044 (0)
GEN3017 (0)
GNC-039 (0)
GNR-084 (0)
HBM7004 (0)
HPN536 (0)
IBI-389 (0)
IGM-2537 (0)
IGM-2644 (0)
IO-312 (0)
ISB 1302 (0)
ISB 2001 (0)
JNJ-6358 (0)
JNJ-63709178 (0)
JNJ-67571244 (0)
JNJ-8543 (0)
JNJ-8902 (0)
JS203 (0)
LBL-033 (0)
FBTA05 (0)
M701 (0)
M802 (0)
MBS314 (0)
MK-6070 (0)
MP0533 (0)
NG-641 (0)
NGM936 (0)
NILK-2301 (0)
NILK-2501 (0)
NM28-2746 (0)
PF-06671008 (0)
PF-07062119 (0)
PF-07260437 (0)
PIT565 (0)
QLS31904 (0)
QLS31905 (0)
QLS32015 (0)
RG6007 (0)
RG6129 (0)
RG6232 (0)
RG6286 (0)
RG6353 (0)
RG6524 (0)
RGV004 (0)
catumaxomab (0)
SAIL66 (0)
SAR440234 (0)
TAK-186 (0)
TQB2825 (0)
TQB2934 (0)
UMG2-CD3 BTCE (0)
Undisclosed HER2Bi-armed ATC (0)
WVT078 (0)
XmAb968 (0)
Y150 (0)
ZG006 (0)
AMG 160 (0)
activated CIK and bispecific antibody (0)
activated CIK-anti-CD3/MUC1/CEA/EpCAM/GPC3 antibody (0)
ARB202 (0)
RG6160 (0)
RG7802 (0)
AMG 330 (0)
AMG 673 (0)
GNC-038 (0)
AMG 596 (0)
RG6234 (0)
AMG 910 (0)
huCD33-BsAb (0)
REGN5458 (0)
APVO436 (0)
GD2xCD3 (0)
MGD009 (0)
AMG 420 (0)
XmAb13676 (0)
JNJ-8780 (0)
RG6194 (0)
AMG 110 (0)
MCLA-117 (0)
XmAb18087 (0)
AMG 199 (0)
REGN5459 (0)
JNJ-6420 (0)
›
Associations
News
Trials
Filter by
Latest
1m
A Study of JNJ-78278343 in Combination With Either JNJ-63723283 (Cetrelimab), Taxane Chemotherapy, or Androgen Receptor Pathway Inhibitors for Metastatic Castration-Resistant Prostate Cancer (clinicaltrials.gov)
P1, N=200, Recruiting, Janssen Research & Development, LLC | N=345 --> 200
1 month ago
Enrollment change
|
docetaxel • Xtandi (enzalutamide capsule) • abiraterone acetate • prednisone • Nubeqa (darolutamide) • cabazitaxel • Erleada (apalutamide) • cetrelimab (JNJ-63723283) • JNJ-8343
4ms
A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer (clinicaltrials.gov)
P1, N=260, Recruiting, Janssen Research & Development, LLC | Trial completion date: Nov 2025 --> Feb 2026
4 months ago
Trial completion date • Metastases
|
JNJ-8343
5ms
A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer (clinicaltrials.gov)
P1, N=260, Recruiting, Janssen Research & Development, LLC | N=165 --> 260
5 months ago
Enrollment change • Metastases
|
JNJ-8343
6ms
A Study of JNJ-78278343 in Combination With Either JNJ-63723283 (Cetrelimab), Taxane Chemotherapy, or Androgen Receptor Pathway Inhibitors for Metastatic Castration-Resistant Prostate Cancer (clinicaltrials.gov)
P1, N=345, Recruiting, Janssen Research & Development, LLC | Trial completion date: Mar 2026 --> Sep 2027
6 months ago
Trial completion date
|
docetaxel • Xtandi (enzalutamide capsule) • abiraterone acetate • prednisone • Nubeqa (darolutamide) • cabazitaxel • Erleada (apalutamide) • cetrelimab (JNJ-63723283) • JNJ-8343
6ms
A Study of JNJ-78278343 in Combination With Either JNJ-63723283 (Cetrelimab), Taxane Chemotherapy, or Androgen Receptor Pathway Inhibitors for Metastatic Castration-Resistant Prostate Cancer (clinicaltrials.gov)
P1, N=345, Recruiting, Janssen Research & Development, LLC | N=20 --> 345
6 months ago
Enrollment change • Combination therapy • Metastases
|
docetaxel • Xtandi (enzalutamide capsule) • abiraterone acetate • prednisone • Nubeqa (darolutamide) • cabazitaxel • Erleada (apalutamide) • cetrelimab (JNJ-63723283) • JNJ-8343
11ms
A Study of JNJ-78278343 in Combination With JNJ-63723283 (Cetrelimab) for Metastatic Castration-Resistant Prostate Cancer (clinicaltrials.gov)
P1, N=20, Recruiting, Janssen Research & Development, LLC | Phase classification: P1b --> P1
11 months ago
Phase classification • Combination therapy • Metastases
|
cetrelimab (JNJ-63723283) • JNJ-8343
1year
A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer (clinicaltrials.gov)
P1, N=165, Recruiting, Janssen Research & Development, LLC | Trial completion date: Nov 2024 --> Nov 2025
1 year ago
Trial completion date • Metastases
|
JNJ-8343
1year
A Study of JNJ-87189401 Plus JNJ-78278343 for Advanced Prostate Cancer (clinicaltrials.gov)
P1, N=110, Recruiting, Janssen Research & Development, LLC | Not yet recruiting --> Recruiting
1 year ago
Enrollment open • Metastases
|
JNJ-8343
1year
A Study of JNJ-87189401 Plus JNJ-78278343 for Advanced Prostate Cancer (clinicaltrials.gov)
P1, N=110, Not yet recruiting, Janssen Research & Development, LLC
1 year ago
New P1 trial • Metastases
|
JNJ-8343
over1year
A Study of JNJ-78278343 in Combination With JNJ-63723283 (Cetrelimab) for Metastatic Castration-Resistant Prostate Cancer (clinicaltrials.gov)
P1b, N=20, Recruiting, Janssen Research & Development, LLC | Not yet recruiting --> Recruiting | N=40 --> 20
over 1 year ago
Enrollment open • Enrollment change
|
cetrelimab (JNJ-63723283) • JNJ-8343
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