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irinotecan liposomal
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Company:
CSPC Pharma
Drug class:
Topoisomerase I inhibitor
Related drugs:
23d
Irinotecan Liposome Combined With Oxaliplatin and Tegafur as Adjuvant Therapy for Pancreatic Cancer (clinicaltrials.gov)
P=N/A, N=53, Recruiting, Kuirong Jiang
New trial
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irinotecan liposomal
2ms
Efficacy and Safety of Irinotecan Liposome Injection Combined With 5-FU/LV± Immunotherapy in First-line Gemsitabine + Immunoprogressive Patients With Metastatic Biliary Tract Cancer (clinicaltrials.gov)
P=N/A, N=30, Recruiting, Tianjin Medical University Cancer Institute and Hospital
New trial
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5-fluorouracil • leucovorin calcium • irinotecan liposomal
3ms
Dose Escalation and Expansion Clinical Trial of Irinotecan Liposome Combined With Oxaliplatin and 5-FU/LV Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer (clinicaltrials.gov)
P1, N=78, Recruiting, Shanghai Zhongshan Hospital
New P1 trial • Metastases
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UGT1A1*1*1
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Avastin (bevacizumab) • Erbitux (cetuximab) • 5-fluorouracil • irinotecan liposomal
over2years
Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer (clinicaltrials.gov)
P2, N=66, Not yet recruiting, CSPC Ouyi Pharmaceutical Co., Ltd. | Trial completion date: Aug 2021 --> Aug 2024 | Trial primary completion date: Aug 2021 --> Aug 2023
Clinical • Trial completion date • Trial primary completion date
|
UGT1A1 (UDP glucuronosyltransferase family 1 member A1)
|
UGT1A1*1*1
|
5-fluorouracil • leucovorin calcium • Enshuxing (enlonstobart) • irinotecan liposomal
over2years
Study of Irinotecan Liposome Injection-containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma (clinicaltrials.gov)
P2, N=153, Not yet recruiting, CSPC Ouyi Pharmaceutical Co., Ltd.
Clinical • New P2 trial
|
UGT1A1 (UDP glucuronosyltransferase family 1 member A1)
|
UGT1A1*1*1
|
gemcitabine • 5-fluorouracil • albumin-bound paclitaxel • oxaliplatin • leucovorin calcium • irinotecan liposomal
over2years
Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer (clinicaltrials.gov)
P2, N=66, Not yet recruiting, CSPC Ouyi Pharmaceutical Co., Ltd.
Clinical • New P2 trial
|
UGT1A1 (UDP glucuronosyltransferase family 1 member A1)
|
UGT1A1*1*1
|
5-fluorouracil • leucovorin calcium • Enshuxing (enlonstobart) • irinotecan liposomal
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