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DRUG:

topotecan

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Company:

Generic mfg.

Drug class:

Topoisomerase I inhibitor

Related drugs:

‹

irinotecan liposomal (0)

topotecan episcleral (0)

fam-trastuzumab deruxtecan-nxki (90)

irinotecan (48)

sacituzumab govitecan-hziy (17)

HRA00129-C004 (3)

nanoliposomal irinotecan (3)

camptothecin nanosomal (1)

HA-irinotecan (0)

ICAM‑1 ADC (0)

etirinotecan pegol (0)

irinotecan liposomal (0)

topotecan episcleral (0)

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No biomarker	Small Cell Lung Cancer	No biomarker	Small Cell Lung Cancer	topotecan Sensitive: A1 - Approval topotecan Sensitive : A1	topotecan Sensitive: A1 - Approval topotecan Sensitive : A1
No biomarker	Ovarian Cancer	No biomarker	Ovarian Cancer	topotecan Sensitive: A1 - Approval topotecan Sensitive : A1	topotecan Sensitive: A1 - Approval topotecan Sensitive : A1
No biomarker	Cervical Cancer	No biomarker	Cervical Cancer	paclitaxel + topotecan Sensitive: A2 - Guideline paclitaxel + topotecan Sensitive : A2	paclitaxel + topotecan Sensitive: A2 - Guideline paclitaxel + topotecan Sensitive : A2
No biomarker	Fallopian Tube Cancer	No biomarker	Fallopian Tube Cancer	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2
No biomarker	Peritoneal Cancer	No biomarker	Peritoneal Cancer	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2
No biomarker	Endometrial Cancer	No biomarker	Endometrial Cancer	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2
No biomarker	Merkel Cell Carcinoma	No biomarker	Merkel Cell Carcinoma	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2
No biomarker	Cervical Cancer	No biomarker	Cervical Cancer	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2
No biomarker	Ewing Sarcoma	No biomarker	Ewing Sarcoma	cyclophosphamide + ifosfamide + etoposide IV + topotecan Sensitive: A2 - Guideline cyclophosphamide + ifosfamide + etoposide IV + topotecan Sensitive : A2	cyclophosphamide + ifosfamide + etoposide IV + topotecan Sensitive: A2 - Guideline cyclophosphamide + ifosfamide + etoposide IV + topotecan Sensitive : A2
No biomarker	Rhabdomyosarcoma	No biomarker	Rhabdomyosarcoma	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2	topotecan Sensitive: A2 - Guideline topotecan Sensitive : A2
No biomarker	Rhabdomyosarcoma	No biomarker	Rhabdomyosarcoma	cyclophosphamide + topotecan Sensitive: A2 - Guideline cyclophosphamide + topotecan Sensitive : A2	cyclophosphamide + topotecan Sensitive: A2 - Guideline cyclophosphamide + topotecan Sensitive : A2
No biomarker	Osteosarcoma	No biomarker	Osteosarcoma	cyclophosphamide + topotecan Sensitive: A2 - Guideline cyclophosphamide + topotecan Sensitive : A2	cyclophosphamide + topotecan Sensitive: A2 - Guideline cyclophosphamide + topotecan Sensitive : A2
No biomarker	Ewing Sarcoma	No biomarker	Ewing Sarcoma	cyclophosphamide + topotecan Sensitive: A2 - Guideline cyclophosphamide + topotecan Sensitive : A2	cyclophosphamide + topotecan Sensitive: A2 - Guideline cyclophosphamide + topotecan Sensitive : A2
No biomarker	Cervical Cancer	No biomarker	Cervical Cancer	cisplatin + topotecan Sensitive: A2 - Guideline cisplatin + topotecan Sensitive : A2	cisplatin + topotecan Sensitive: A2 - Guideline cisplatin + topotecan Sensitive : A2
No biomarker	Small Cell Lung Cancer	No biomarker	Small Cell Lung Cancer	cisplatin + topotecan Sensitive: A2 - Guideline cisplatin + topotecan Sensitive : A2	cisplatin + topotecan Sensitive: A2 - Guideline cisplatin + topotecan Sensitive : A2
ABCG2 overexpression	Solid Tumor	ABCG2 overexpression	Solid Tumor	topotecan + TP-3654 Sensitive: D – Preclinical topotecan + TP-3654 Sensitive : D	topotecan + TP-3654 Sensitive: D – Preclinical topotecan + TP-3654 Sensitive : D