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DRUG:

DS-6157

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Company:

Daiichi Sankyo

Drug class:

Topoisomerase I inhibitor, GPR20 -targeted antibody-drug conjugate

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topotecan episcleral (0)

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KIT wild-type	Gastrointestinal Stromal Tumor	KIT wild-type	Gastrointestinal Stromal Tumor	DS-6157 Sensitive: C3 – Early Trials DS-6157 Sensitive : C3	DS-6157 Sensitive: C3 – Early Trials DS-6157 Sensitive : C3
SDHB mutation + NF1 mutation	Gastrointestinal Stromal Tumor	SDHB mutation + NF1 mutation	Gastrointestinal Stromal Tumor	DS-6157 Sensitive: C4 – Case Studies DS-6157 Sensitive : C4	DS-6157 Sensitive: C4 – Case Studies DS-6157 Sensitive : C4
GPR20 expression	Gastrointestinal Stromal Tumor	GPR20 expression	Gastrointestinal Stromal Tumor	DS-6157 Sensitive: D – Preclinical DS-6157 Sensitive : D	DS-6157 Sensitive: D – Preclinical DS-6157 Sensitive : D