Tumor Mutational Burden • PD(L)-1 Biomarker • IO biomarker
|
PD-L1 (Programmed death ligand 1) • TP53 (Tumor protein P53) • TMB (Tumor Mutational Burden) • HRAS (Harvey rat sarcoma viral oncogene homolog) • CD8 (cluster of differentiation 8) • IFNG (Interferon, gamma) • LAG3 (Lymphocyte Activating 3) • CD123 (Interleukin 3 Receptor Subunit Alpha) • IDO1 (Indoleamine 2,3-dioxygenase 1) • IRF1 (Interferon Regulatory Factor 1)
|
TP53 mutation • IRF1 expression
|
flotetuzumab (MGD006)