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DRUG:

AFM11

i
Other names: AFM11, AFM11 TandAb, CD19 x CD3 TandAb
Associations
Trials
Company:
Affimed
Drug class:
CD3 agonist, CD19 inhibitor
Related drugs:
Associations
Trials
over1year
Safety of AFM11 in the treatment of patients with B-cell malignancies: findings from two phase 1 studies. (PubMed, Trials)
AFM11 treatment was associated with frequent neurological adverse reactions that were severe in some patients. In ALL, some signs of activity, albeit short-lived, were observed whereas no activity was observed in patients with NHL; therefore, further clinical development was terminated.
P1 data • Journal
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CD19 (CD19 Molecule)
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CD19 positive
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AFM11