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DRUG:
sirolimus
i
Other names:
AY 22989, NSC 226080, NPC-12
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Associations
(20)
News
Trials
Company:
Generic mfg.
Drug class:
mTOR inhibitor
Related drugs:
‹
everolimus (138)
RTB101 (43)
temsirolimus (37)
PF-05212384 (31)
GSK2126458 (17)
AZD8055 (10)
PF-04691502 (6)
LY3023414 (5)
GDC-0980 (4)
phenformin (4)
AZD2014 (4)
CC-115 (3)
RapaLink-1 (3)
GDC-0084 (3)
AVTX-006 (2)
ME-344 (2)
PI-103 (2)
Torin1 (2)
PP242 (2)
DFN-529 (1)
EC-70124 (1)
QL-VIII-58 (1)
niclosamide (1)
CBL0102 (1)
AUM302 (0)
BGT226 (0)
DS-3078 (0)
DS-7423 (0)
DTRM-555 (0)
ETP-47187 (0)
HEC68498 (0)
IBL-301 (0)
MKC-1 (0)
rapamycin topical (0)
SF1126 (0)
ridaforolimus (0)
VCD-597 (0)
VS-5584 (0)
XL388 (0)
PQR309 (0)
NSC311152 (0)
encapsulated rapamycin (0)
everolimus (0)
SVG101 (0)
ABTL0812 (0)
inhibitors of the PI3K/AKT/mTOR pathway (0)
KD 032 (0)
albumin-bound (0)
SAR245409 (0)
everolimus (138)
RTB101 (43)
temsirolimus (37)
PF-05212384 (31)
GSK2126458 (17)
AZD8055 (10)
PF-04691502 (6)
LY3023414 (5)
GDC-0980 (4)
phenformin (4)
AZD2014 (4)
CC-115 (3)
RapaLink-1 (3)
GDC-0084 (3)
AVTX-006 (2)
ME-344 (2)
PI-103 (2)
Torin1 (2)
PP242 (2)
DFN-529 (1)
EC-70124 (1)
QL-VIII-58 (1)
niclosamide (1)
CBL0102 (1)
AUM302 (0)
BGT226 (0)
DS-3078 (0)
DS-7423 (0)
DTRM-555 (0)
ETP-47187 (0)
HEC68498 (0)
IBL-301 (0)
MKC-1 (0)
rapamycin topical (0)
SF1126 (0)
ridaforolimus (0)
VCD-597 (0)
VS-5584 (0)
XL388 (0)
PQR309 (0)
NSC311152 (0)
encapsulated rapamycin (0)
everolimus (0)
SVG101 (0)
ABTL0812 (0)
inhibitors of the PI3K/AKT/mTOR pathway (0)
KD 032 (0)
albumin-bound (0)
SAR245409 (0)
›
Associations
(20)
News
Trials
VERI cancer hierarchy
Reset Filters
No biomarker
Hepatocellular Cancer
No biomarker
Hepatocellular Cancer
sirolimus
Sensitive: A2 - Guideline
sirolimus
Sensitive
:
A2
sirolimus
Sensitive: A2 - Guideline
sirolimus
Sensitive
:
A2
No biomarker
Kaposi Sarcoma
No biomarker
Kaposi Sarcoma
sirolimus
Sensitive: A2 - Guideline
sirolimus
Sensitive
:
A2
sirolimus
Sensitive: A2 - Guideline
sirolimus
Sensitive
:
A2
No biomarker
Soft Tissue Sarcoma
No biomarker
Soft Tissue Sarcoma
sirolimus
Sensitive: A2 - Guideline
sirolimus
Sensitive
:
A2
sirolimus
Sensitive: A2 - Guideline
sirolimus
Sensitive
:
A2
MYCN positive
Neuroblastoma
MYCN positive
Neuroblastoma
dasatinib + temozolomide + sirolimus
Sensitive: C3 – Early Trials
dasatinib + temozolomide + sirolimus
Sensitive
:
C3
dasatinib + temozolomide + sirolimus
Sensitive: C3 – Early Trials
dasatinib + temozolomide + sirolimus
Sensitive
:
C3
PIK3CA mutation + HR positive
HER2 Positive Breast Cancer
PIK3CA mutation + HR positive
HER2 Positive Breast Cancer
sirolimus + inetetamab
Sensitive: C4 – Case Studies
sirolimus + inetetamab
Sensitive
:
C4
sirolimus + inetetamab
Sensitive: C4 – Case Studies
sirolimus + inetetamab
Sensitive
:
C4
NCOR1-LYN fusion
B Acute Lymphoblastic Leukemia
NCOR1-LYN fusion
B Acute Lymphoblastic Leukemia
sirolimus
Resistant: D – Preclinical
sirolimus
Resistant
:
D
sirolimus
Resistant: D – Preclinical
sirolimus
Resistant
:
D
KRAS G12D + TP53 deletion
Lung Adenocarcinoma
KRAS G12D + TP53 deletion
Lung Adenocarcinoma
sirolimus + IPI-504
Sensitive: D – Preclinical
sirolimus + IPI-504
Sensitive
:
D
sirolimus + IPI-504
Sensitive: D – Preclinical
sirolimus + IPI-504
Sensitive
:
D
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
KRAS mutation
Non Small Cell Lung Cancer
KRAS mutation
Non Small Cell Lung Cancer
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
NOTCH1 expression
Acute Lymphocytic Leukemia
NOTCH1 expression
Acute Lymphocytic Leukemia
sirolimus + MRK003
Sensitive: D – Preclinical
sirolimus + MRK003
Sensitive
:
D
sirolimus + MRK003
Sensitive: D – Preclinical
sirolimus + MRK003
Sensitive
:
D
TP53 deletion
Colorectal Cancer
TP53 deletion
Colorectal Cancer
sirolimus + IPI-504
Sensitive: D – Preclinical
sirolimus + IPI-504
Sensitive
:
D
sirolimus + IPI-504
Sensitive: D – Preclinical
sirolimus + IPI-504
Sensitive
:
D
MTOR F2108L
Thyroid Gland Carcinoma
MTOR F2108L
Thyroid Gland Carcinoma
sirolimus
Resistant: D – Preclinical
sirolimus
Resistant
:
D
sirolimus
Resistant: D – Preclinical
sirolimus
Resistant
:
D
TP53 deletion
Non Small Cell Lung Cancer
TP53 deletion
Non Small Cell Lung Cancer
sirolimus + IPI-504
Sensitive: D – Preclinical
sirolimus + IPI-504
Sensitive
:
D
sirolimus + IPI-504
Sensitive: D – Preclinical
sirolimus + IPI-504
Sensitive
:
D
EPHA2 G391R
Non Small Cell Lung Cancer
EPHA2 G391R
Non Small Cell Lung Cancer
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
ROR1 expression
Cervical Cancer
ROR1 expression
Cervical Cancer
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
JAK2 R683G
Acute Lymphocytic Leukemia
JAK2 R683G
Acute Lymphocytic Leukemia
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
TP53 mutation
Medulloblastoma
TP53 mutation
Medulloblastoma
AN2025 + sirolimus
Sensitive: D – Preclinical
AN2025 + sirolimus
Sensitive
:
D
AN2025 + sirolimus
Sensitive: D – Preclinical
AN2025 + sirolimus
Sensitive
:
D
GNA13 deletion + KRAS mutation
Pancreatic Cancer
GNA13 deletion + KRAS mutation
Pancreatic Cancer
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
KRAS mutation + TP53 mutation + GNA13 deletion
Pancreatic Cancer
KRAS mutation + TP53 mutation + GNA13 deletion
Pancreatic Cancer
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
GNA13 deletion + TP53 mutation
Pancreatic Cancer
GNA13 deletion + TP53 mutation
Pancreatic Cancer
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
sirolimus
Sensitive: D – Preclinical
sirolimus
Sensitive
:
D
^
^
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