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BIOMARKER:

RB1 mutation

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Other names: RB1, Retinoblastoma 1, RB Transcriptional Corepressor 1, Protein Phosphatase 1, Regulatory Subunit 130, Prepro-Retinoblastoma-Associated Protein, Retinoblastoma-Associated Protein, Retinoblastoma-Associated Protein, Retinoblastoma Suspectibility Protein
Entrez ID:
Related biomarkers:
RB1 mutation
Urothelial Cancer
pembrolizumab
Sensitive: C3 – Early Trials
RB1 mutation
Bladder Cancer
pembrolizumab
Sensitive: C3 – Early Trials
RB1 mutation
Small Cell Lung Cancer
nivolumab
Resistant: C3 – Early Trials
RB1 mutation
Prostate Cancer
AST-2970
Resistant: C3 – Early Trials
RB1 mutation
Prostate Cancer
docetaxel
Resistant: C3 – Early Trials
RB1 mutation
Triple Negative Breast Cancer
carboplatin + docetaxel
Sensitive: C3 – Early Trials
RB1 mutation
Ovarian Cancer
carboplatin + paclitaxel
Resistant: C3 – Early Trials
RB1 mutation
Prostate Cancer
cyclophosphamide oral + dexamethasone
Sensitive: C4 – Case Studies
RB1 mutation
Meningioma
palbociclib
Sensitive: D – Preclinical
RB1 mutation
Ovarian Cancer
abemaciclib
Resistant: D – Preclinical
RB1 mutation
Small Cell Lung Cancer
nivolumab + ipilimumab
Resistant: D – Preclinical