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Association details:
Biomarker:
RB1 mutation
Cancer:
Prostate Cancer
Drug:
docetaxel
(
Tubulin polymerization promoter
,
Microtubule stabilizer
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
J Natl Compr Canc Netw
Title:
Use of Circulating Tumor DNA for the Clinical Management of Metastatic Castration-Resistant Prostate Cancer: A Multicenter, Real-World Study
Published date:
05/14/2021
Excerpt:
AR amplification and TP53 and/or RB1 alterations were associated with resistance to abiraterone or docetaxel.
DOI:
10.6004/jnccn.2020.7663
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