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BIOMARKER:
RAS wild-type
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Entrez ID:
3845
;
4893
;
3265
Related biomarkers:
Expression
Mutation
CNA
Others
‹
STK11 deletion + KRAS mutation (6)
FGF19 amplification + HRAS Q61R + TP53 672+2T>G (6)
FGF3 amplification + HRAS Q61R + TP53 672+2T>G (6)
FGF4 amplification + HRAS Q61R + TP53 672+2T>G (6)
KRAS G12C + PD-L1 overexpression (4)
KRAS mutation + PD-L1 expression (4)
CPS1 overexpression + KRAS mutation + STK11 mutation (3)
HER-2 amplification + KRAS G12D (3)
KEAP1 deletion + KRAS mutation (3)
PD-L1 overexpression + KRAS mutation (3)
EGFR exon 19 deletion + NRAS Q61K (3)
EGFR exon 19 deletion + KRAS mutation (2)
KRAS G12C + PD-L1 underexpression (2)
KRAS mutation + PD-L1 negative (2)
MSI-L/dMMR + KRAS G12V (2)
PD-L1 expression + NRAS Q61R + BRAF D594N (2)
AXL overexpression + KRAS G12C (1)
CDH2 overexpression + KRAS wild-type (1)
Chr t(11;14) + KRAS mutation (1)
EGFR C797S + KRAS amplification + RB1 deletion (1)
EGFR L858R + KRAS amplification + RB1 deletion (1)
EGFR T790M + KRAS amplification + RB1 deletion (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
EGFR exon 19 deletion + TP53 mutation + CDK6 amplification + KRAS amplification (1)
EGFR expression + KRAS G12C (1)
EGFR overexpression + KRAS 13D (1)
EGFR overexpression + KRAS mutation (1)
FGFR1 overexpression + KRAS G12C (1)
GNA13 deletion + KRAS mutation (1)
GOPC-ROS1 fusion + KRAS Q61H (1)
HER-2 amplification + KRAS exon 2 wild-type (1)
HER-2 amplification + KRAS wild-type (1)
HER-2 overexpression + KRAS wild-type (1)
IGF1R overexpression + KRAS mutation (1)
IR overexpression + KRAS mutation (1)
IRS2 amplification + KRAS mutation (1)
KEAP1 mutation + KRAS wild-type (1)
KRAS A146 + TMB-H (1)
KRAS G12C + PD-L1 expression (1)
KRAS G12C + PD-L1 underexpression + STK11 mutation (1)
KRAS G12D + Chr del(9)(p21) (1)
KRAS G12D + HER-2 amplification + TMB-H (1)
KRAS G12D + TP53 deletion (1)
KRAS amplification + BRAF wild-type (1)
KRAS amplification + RAS wild-type (1)
KRAS mutation + PTPN11 overexpression + PD-L1 overexpression (1)
KRAS mutation + BCL2A1 overexpression (1)
KRAS mutation + CDK9 overexpression + HR positive (1)
KRAS mutation + EGFR amplification (1)
KRAS mutation + ER expression (1)
KRAS mutation + HER-2 positive (1)
KRAS mutation + HR positive (1)
KRAS mutation + PD-L1 underexpression (1)
KRAS mutation + PIK3CA wild-type (1)
KRAS mutation + PTPN11 overexpression (1)
KRAS mutation + TP53 mutation + GNA13 deletion (1)
KRAS mutation + TP53 mutation + PD-L1 expression + PD-1 expression (1)
KRAS mutation + YKL-40 overexpression (1)
KRAS wild-type + BRAF V600E (1)
KRAS wild-type + NRAS wild-type + MSI-H/dMMR (1)
KRAS mutation + STK11 mutation + AXL expression (1)
MLL-AFF1 fusion + KRAS mutation (1)
MSI-H/dMMR + KRAS G12D (1)
MSI-H/dMMR + KRAS Mutation (1)
MSI-H/dMMR + KRAS wild-type + BRAF wild-type (1)
MTAP deletion + KRAS G12C (1)
PD-L1 negative + KRAS G12C (1)
PD-L1 overexpression + KRAS G12C + TP53 mutation (1)
POMK-NRG1 fusion + KRAS mutation (1)
POMK‐NRG1 fusion + KRAS G12D (1)
PTEN deletion + KRAS G12C (1)
RET positive + KRAS G12V (1)
ROS1 fusion + KRAS G12C (1)
STK11 mutation + KRAS mutation + TP53 deletion (1)
STRN-ALK fusion + KRAS G13D (1)
TP53 S12F + KRAS G12D + TMB-L (1)
CDKN2A Negative + NRAS Mutation (1)
Chr t(11;14) + NRAS mutation (1)
MLL-AFF1 fusion + NRAS mutation (1)
NRAS mutation + BRAF wild-type (1)
NRAS wild-type + NOTCH4 mutation (1)
HRAS Q61R + TP53 P278S + PD-L1 overexpression (1)
HRAS overexpression + PIK3CA amplification (1)
HRAS overexpression + PIK3CA mutation (1)
HER-2 amplification + KRAS G12C (0)
PRMT5 overexpression + KRAS mutation (0)
STK11 deletion + KRAS mutation (6)
FGF19 amplification + HRAS Q61R + TP53 672+2T>G (6)
FGF3 amplification + HRAS Q61R + TP53 672+2T>G (6)
FGF4 amplification + HRAS Q61R + TP53 672+2T>G (6)
KRAS G12C + PD-L1 overexpression (4)
KRAS mutation + PD-L1 expression (4)
CPS1 overexpression + KRAS mutation + STK11 mutation (3)
HER-2 amplification + KRAS G12D (3)
KEAP1 deletion + KRAS mutation (3)
PD-L1 overexpression + KRAS mutation (3)
EGFR exon 19 deletion + NRAS Q61K (3)
EGFR exon 19 deletion + KRAS mutation (2)
KRAS G12C + PD-L1 underexpression (2)
KRAS mutation + PD-L1 negative (2)
MSI-L/dMMR + KRAS G12V (2)
PD-L1 expression + NRAS Q61R + BRAF D594N (2)
AXL overexpression + KRAS G12C (1)
CDH2 overexpression + KRAS wild-type (1)
Chr t(11;14) + KRAS mutation (1)
EGFR C797S + KRAS amplification + RB1 deletion (1)
EGFR L858R + KRAS amplification + RB1 deletion (1)
EGFR T790M + KRAS amplification + RB1 deletion (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
EGFR exon 19 deletion + TP53 mutation + CDK6 amplification + KRAS amplification (1)
EGFR expression + KRAS G12C (1)
EGFR overexpression + KRAS 13D (1)
EGFR overexpression + KRAS mutation (1)
FGFR1 overexpression + KRAS G12C (1)
GNA13 deletion + KRAS mutation (1)
GOPC-ROS1 fusion + KRAS Q61H (1)
HER-2 amplification + KRAS exon 2 wild-type (1)
HER-2 amplification + KRAS wild-type (1)
HER-2 overexpression + KRAS wild-type (1)
IGF1R overexpression + KRAS mutation (1)
IR overexpression + KRAS mutation (1)
IRS2 amplification + KRAS mutation (1)
KEAP1 mutation + KRAS wild-type (1)
KRAS A146 + TMB-H (1)
KRAS G12C + PD-L1 expression (1)
KRAS G12C + PD-L1 underexpression + STK11 mutation (1)
KRAS G12D + Chr del(9)(p21) (1)
KRAS G12D + HER-2 amplification + TMB-H (1)
KRAS G12D + TP53 deletion (1)
KRAS amplification + BRAF wild-type (1)
KRAS amplification + RAS wild-type (1)
KRAS mutation + PTPN11 overexpression + PD-L1 overexpression (1)
KRAS mutation + BCL2A1 overexpression (1)
KRAS mutation + CDK9 overexpression + HR positive (1)
KRAS mutation + EGFR amplification (1)
KRAS mutation + ER expression (1)
KRAS mutation + HER-2 positive (1)
KRAS mutation + HR positive (1)
KRAS mutation + PD-L1 underexpression (1)
KRAS mutation + PIK3CA wild-type (1)
KRAS mutation + PTPN11 overexpression (1)
KRAS mutation + TP53 mutation + GNA13 deletion (1)
KRAS mutation + TP53 mutation + PD-L1 expression + PD-1 expression (1)
KRAS mutation + YKL-40 overexpression (1)
KRAS wild-type + BRAF V600E (1)
KRAS wild-type + NRAS wild-type + MSI-H/dMMR (1)
KRAS mutation + STK11 mutation + AXL expression (1)
MLL-AFF1 fusion + KRAS mutation (1)
MSI-H/dMMR + KRAS G12D (1)
MSI-H/dMMR + KRAS Mutation (1)
MSI-H/dMMR + KRAS wild-type + BRAF wild-type (1)
MTAP deletion + KRAS G12C (1)
PD-L1 negative + KRAS G12C (1)
PD-L1 overexpression + KRAS G12C + TP53 mutation (1)
POMK-NRG1 fusion + KRAS mutation (1)
POMK‐NRG1 fusion + KRAS G12D (1)
PTEN deletion + KRAS G12C (1)
RET positive + KRAS G12V (1)
ROS1 fusion + KRAS G12C (1)
STK11 mutation + KRAS mutation + TP53 deletion (1)
STRN-ALK fusion + KRAS G13D (1)
TP53 S12F + KRAS G12D + TMB-L (1)
CDKN2A Negative + NRAS Mutation (1)
Chr t(11;14) + NRAS mutation (1)
MLL-AFF1 fusion + NRAS mutation (1)
NRAS mutation + BRAF wild-type (1)
NRAS wild-type + NOTCH4 mutation (1)
HRAS Q61R + TP53 P278S + PD-L1 overexpression (1)
HRAS overexpression + PIK3CA amplification (1)
HRAS overexpression + PIK3CA mutation (1)
HER-2 amplification + KRAS G12C (0)
PRMT5 overexpression + KRAS mutation (0)
›
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
regorafenib
Sensitive: A1 - Approval
regorafenib
Sensitive
:
A1
regorafenib
Sensitive: A1 - Approval
regorafenib
Sensitive
:
A1
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
panitumumab
Sensitive: A1 - Approval
panitumumab
Sensitive
:
A1
panitumumab
Sensitive: A1 - Approval
panitumumab
Sensitive
:
A1
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
cetuximab
Sensitive: A2 - Guideline
cetuximab
Sensitive
:
A2
cetuximab
Sensitive: A2 - Guideline
cetuximab
Sensitive
:
A2
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
fruquintinib
Sensitive: B - Late Trials
fruquintinib
Sensitive
:
B
fruquintinib
Sensitive: B - Late Trials
fruquintinib
Sensitive
:
B
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
bevacizumab
Sensitive: B - Late Trials
bevacizumab
Sensitive
:
B
bevacizumab
Sensitive: B - Late Trials
bevacizumab
Sensitive
:
B
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
ramucirumab
Sensitive: C2 – Inclusion Criteria
ramucirumab
Sensitive
:
C2
ramucirumab
Sensitive: C2 – Inclusion Criteria
ramucirumab
Sensitive
:
C2
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
bevacizumab + cetuximab
Sensitive: C2 – Inclusion Criteria
bevacizumab + cetuximab
Sensitive
:
C2
bevacizumab + cetuximab
Sensitive: C2 – Inclusion Criteria
bevacizumab + cetuximab
Sensitive
:
C2
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
cetuximab + avelumab
Sensitive: C2 – Inclusion Criteria
cetuximab + avelumab
Sensitive
:
C2
cetuximab + avelumab
Sensitive: C2 – Inclusion Criteria
cetuximab + avelumab
Sensitive
:
C2
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
cetuximab + camrelizumab
Sensitive: C2 – Inclusion Criteria
cetuximab + camrelizumab
Sensitive
:
C2
cetuximab + camrelizumab
Sensitive: C2 – Inclusion Criteria
cetuximab + camrelizumab
Sensitive
:
C2
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
EGFR inhibitor
Sensitive: C3 – Early Trials
EGFR inhibitor
Sensitive
:
C3
EGFR inhibitor
Sensitive: C3 – Early Trials
EGFR inhibitor
Sensitive
:
C3
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
avelumab
Sensitive: C3 – Early Trials
avelumab
Sensitive
:
C3
avelumab
Sensitive: C3 – Early Trials
avelumab
Sensitive
:
C3
RAS wild-type
Colon Cancer
RAS wild-type
Colon Cancer
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
cetuximab
Resistant: C3 – Early Trials
cetuximab
Resistant
:
C3
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
anlotinib
Sensitive: C3 – Early Trials
anlotinib
Sensitive
:
C3
anlotinib
Sensitive: C3 – Early Trials
anlotinib
Sensitive
:
C3
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
cetuximab + tislelizumab-jsgr
Sensitive: C3 – Early Trials
cetuximab + tislelizumab-jsgr
Sensitive
:
C3
cetuximab + tislelizumab-jsgr
Sensitive: C3 – Early Trials
cetuximab + tislelizumab-jsgr
Sensitive
:
C3
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
EGFR inhibitor + VEGF inhibitor
Sensitive: C3 – Early Trials
EGFR inhibitor + VEGF inhibitor
Sensitive
:
C3
EGFR inhibitor + VEGF inhibitor
Sensitive: C3 – Early Trials
EGFR inhibitor + VEGF inhibitor
Sensitive
:
C3
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
panitumumab + cabozantinib tablet
Sensitive: C3 – Early Trials
panitumumab + cabozantinib tablet
Sensitive
:
C3
panitumumab + cabozantinib tablet
Sensitive: C3 – Early Trials
panitumumab + cabozantinib tablet
Sensitive
:
C3
RAS wild-type
Colorectal Cancer
RAS wild-type
Colorectal Cancer
panitumumab + niraparib
Sensitive: C3 – Early Trials
panitumumab + niraparib
Sensitive
:
C3
panitumumab + niraparib
Sensitive: C3 – Early Trials
panitumumab + niraparib
Sensitive
:
C3
^
^
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