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BIOMARKER:

FGF3 amplification + HRAS Q61R + TP53 672+2T>G

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Other names: TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1, HRAS, HRAS1, Harvey rat sarcoma viral oncogene homolog, FGF3, Fibroblast Growth Factor 3, V-INT2 Murine Mammary Tumor Virus Integration Site Oncogene Homolog, Murine Mammary Tumor Virus Integration Site 2, Heparin-Binding Growth Factor 3, INT-2 Proto-Oncogene Protein, Proto-Oncogene Int-2, Oncogene INT2, HBGF-3, INT2
Entrez ID:
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Trials
FGF3 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
APR-246
Sensitive: D – Preclinical
FGF3 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
MK-2206
Sensitive: D – Preclinical
FGF3 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
tipifarnib
Sensitive: D – Preclinical
FGF3 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
erdafitinib
Sensitive: D – Preclinical
FGF3 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
INNO-406
Sensitive: D – Preclinical
FGF3 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
abemaciclib
Sensitive: D – Preclinical