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BIOMARKER:

FGF4 amplification + HRAS Q61R + TP53 672+2T>G

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Other names: TP53, Tumor Protein P53, Cellular Tumor Antigen P53, Phosphoprotein P53, Tumor Protein P53, Antigen NY-CO-13, Transformation-Related Protein 53, Mutant Tumor Protein 53, P53 Tumor Suppressor, Tumor Suppressor P53, Tumor Protein 53, BMFS5, TRP53, BCC7, LFS1, HRAS, HRAS1, Harvey rat sarcoma viral oncogene homolog, FGF4, Fibroblast Growth Factor 4, Transforming Protein KS3, Human Stomach Cancer, Transforming Factor From FGF-Related Oncogene, Heparin Secretory Transforming Protein 1, Heparin-Binding Growth Factor 4, HBGF-4, HSTF-1, FGF-4, HST-1, Fibroblast Growth Factor 4 Splice Isoform, Heparin Secretory-Transforming Protein 1
Entrez ID:
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Trials
FGF4 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
abemaciclib
Sensitive: D – Preclinical
FGF4 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
INNO-406
Sensitive: D – Preclinical
FGF4 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
erdafitinib
Sensitive: D – Preclinical
FGF4 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
tipifarnib
Sensitive: D – Preclinical
FGF4 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
MK-2206
Sensitive: D – Preclinical
FGF4 amplification + HRAS Q61R + TP53 672+2T>G
Prostate Cancer
APR-246
Sensitive: D – Preclinical