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BIOMARKER:
PD-L1 expression + EGFR mutation
i
Other names:
PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule, EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
;
29126
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR exon 19 deletion (79)
EGFR amplification (52)
PD-L1 amplification (6)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
PD-L1 deletion (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
EGFR exon 19 deletion (79)
EGFR amplification (52)
PD-L1 amplification (6)
EGFR exon 18 deletion (3)
EGFR exon 2-7 deletion + EGFR amplification (2)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
EGFR exon 21 deletion (1)
PD-L1 deletion (1)
EGFR T790M + exon 19 deletion (0)
EGFR amplifcation (0)
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VERI cancer hierarchy
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PD-L1 expression + EGFR mutation
Non Small Cell Lung Cancer
PD-L1 expression + EGFR mutation
Non Small Cell Lung Cancer
EGFR inhibitor
Resistant: C3 – Early Trials
EGFR inhibitor
Resistant
:
C3
EGFR inhibitor
Resistant: C3 – Early Trials
EGFR inhibitor
Resistant
:
C3
PD-L1 expression + EGFR mutation
Non Small Cell Lung Cancer
PD-L1 expression + EGFR mutation
Non Small Cell Lung Cancer
PD-L1 inhibitor
Resistant: C3 – Early Trials
PD-L1 inhibitor
Resistant
:
C3
PD-L1 inhibitor
Resistant: C3 – Early Trials
PD-L1 inhibitor
Resistant
:
C3
PD-L1 expression + EGFR mutation
Non Small Cell Lung Cancer
PD-L1 expression + EGFR mutation
Non Small Cell Lung Cancer
aumolertinib
Sensitive: C3 – Early Trials
aumolertinib
Sensitive
:
C3
aumolertinib
Sensitive: C3 – Early Trials
aumolertinib
Sensitive
:
C3
PD-L1 expression + EGFR mutation
Non Small Cell Lung Cancer
PD-L1 expression + EGFR mutation
Non Small Cell Lung Cancer
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
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