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BIOMARKER:
MET amplification + EGFR mutation
i
Other names:
DFNB97, AUTS9, RCCP2, C-Met, HGFR, HGF Receptor, Met Proto-Oncogene, HGF/SF Receptor, Proto-Oncogene C-Met, Scatter Factor Receptor, Tyrosine-Protein Kinase Met, Hepatocyte Growth Factor Receptor, MET, MET Proto-Oncogene, Receptor Tyrosine Kinase, EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
;
4233
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR expression (46)
EGFR overexpression (34)
MET overexpression (32)
MET expression (12)
EGFR positive (8)
MET positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
MET overexpression + KDR overexpression (2)
MET overexpression + SYK overexpression (2)
TPBG expression + MET expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
FGFR overexpression + MET overexpression (1)
MET expression + HER-2 expression (1)
MET overexpression + HER-2 overexpression (1)
MET overexpression + MUC5B overexpression (1)
MET underexpression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
PTGS2 positive + MET positive + TOPK positive + EGFR mutation (0)
EGFR expression (46)
EGFR overexpression (34)
MET overexpression (32)
MET expression (12)
EGFR positive (8)
MET positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
MET overexpression + KDR overexpression (2)
MET overexpression + SYK overexpression (2)
TPBG expression + MET expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
FGFR overexpression + MET overexpression (1)
MET expression + HER-2 expression (1)
MET overexpression + HER-2 overexpression (1)
MET overexpression + MUC5B overexpression (1)
MET underexpression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
PTGS2 positive + MET positive + TOPK positive + EGFR mutation (0)
›
Associations
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MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
crizotinib
Sensitive: C3 – Early Trials
crizotinib
Sensitive
:
C3
crizotinib
Sensitive: C3 – Early Trials
crizotinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
gefitinib + capmatinib
Sensitive: C3 – Early Trials
gefitinib + capmatinib
Sensitive
:
C3
gefitinib + capmatinib
Sensitive: C3 – Early Trials
gefitinib + capmatinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib + savolitinib
Sensitive: C3 – Early Trials
osimertinib + savolitinib
Sensitive
:
C3
osimertinib + savolitinib
Sensitive: C3 – Early Trials
osimertinib + savolitinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib + tepotinib
Sensitive: C3 – Early Trials
osimertinib + tepotinib
Sensitive
:
C3
osimertinib + tepotinib
Sensitive: C3 – Early Trials
osimertinib + tepotinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib + capmatinib
Sensitive: C3 – Early Trials
osimertinib + capmatinib
Sensitive
:
C3
osimertinib + capmatinib
Sensitive: C3 – Early Trials
osimertinib + capmatinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib
Resistant: D – Preclinical
osimertinib
Resistant
:
D
osimertinib
Resistant: D – Preclinical
osimertinib
Resistant
:
D
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
lazertinib + ABN401
Sensitive: D – Preclinical
lazertinib + ABN401
Sensitive
:
D
lazertinib + ABN401
Sensitive: D – Preclinical
lazertinib + ABN401
Sensitive
:
D
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