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BIOMARKER:
MET amplification + EGFR mutation
i
Other names:
DFNB97, AUTS9, RCCP2, C-Met, HGFR, HGF Receptor, Met Proto-Oncogene, HGF/SF Receptor, Proto-Oncogene C-Met, Scatter Factor Receptor, Tyrosine-Protein Kinase Met, Hepatocyte Growth Factor Receptor, MET, MET Proto-Oncogene, Receptor Tyrosine Kinase, EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
;
4233
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR-RAD51 fusion (5)
HLA-DRB1-MET fusion (3)
EGFR-SEPTIN14 fusion (2)
KIF5B-MET fusion (2)
MET fusion (2)
MET-ATXN7L1 fusion (2)
EGFR fusion (1)
EGFR-GRB2 fusion (1)
KIF5B-EGFR fusion (1)
CD47-MET fusion (1)
EHBP1‐MET fusion (1)
KIF5B-MET fusion + MET-CDR2 fusion (1)
MET-TNS3 fusion (1)
MET-TRIM4 fusion (1)
MET-UBE2H fusion (1)
PRKAR1A-MET fusion (1)
RBPMS-MET fusion (1)
STARD3NL-MET fusion (1)
EGFR fusion + RAD51 fusion (0)
EGFR-RAD51 fusion (5)
HLA-DRB1-MET fusion (3)
EGFR-SEPTIN14 fusion (2)
KIF5B-MET fusion (2)
MET fusion (2)
MET-ATXN7L1 fusion (2)
EGFR fusion (1)
EGFR-GRB2 fusion (1)
KIF5B-EGFR fusion (1)
CD47-MET fusion (1)
EHBP1‐MET fusion (1)
KIF5B-MET fusion + MET-CDR2 fusion (1)
MET-TNS3 fusion (1)
MET-TRIM4 fusion (1)
MET-UBE2H fusion (1)
PRKAR1A-MET fusion (1)
RBPMS-MET fusion (1)
STARD3NL-MET fusion (1)
EGFR fusion + RAD51 fusion (0)
›
Associations
News
Trials
VERI cancer hierarchy
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MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
gefitinib + tepotinib
Sensitive: C3 – Early Trials
gefitinib + tepotinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
crizotinib
Sensitive: C3 – Early Trials
crizotinib
Sensitive
:
C3
crizotinib
Sensitive: C3 – Early Trials
crizotinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
gefitinib + capmatinib
Sensitive: C3 – Early Trials
gefitinib + capmatinib
Sensitive
:
C3
gefitinib + capmatinib
Sensitive: C3 – Early Trials
gefitinib + capmatinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib + savolitinib
Sensitive: C3 – Early Trials
osimertinib + savolitinib
Sensitive
:
C3
osimertinib + savolitinib
Sensitive: C3 – Early Trials
osimertinib + savolitinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib + tepotinib
Sensitive: C3 – Early Trials
osimertinib + tepotinib
Sensitive
:
C3
osimertinib + tepotinib
Sensitive: C3 – Early Trials
osimertinib + tepotinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib + capmatinib
Sensitive: C3 – Early Trials
osimertinib + capmatinib
Sensitive
:
C3
osimertinib + capmatinib
Sensitive: C3 – Early Trials
osimertinib + capmatinib
Sensitive
:
C3
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
osimertinib
Resistant: D – Preclinical
osimertinib
Resistant
:
D
osimertinib
Resistant: D – Preclinical
osimertinib
Resistant
:
D
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
MET amplification + EGFR mutation
Non Small Cell Lung Cancer
lazertinib + ABN401
Sensitive: D – Preclinical
lazertinib + ABN401
Sensitive
:
D
lazertinib + ABN401
Sensitive: D – Preclinical
lazertinib + ABN401
Sensitive
:
D
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