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DRUG:
JQ-1
i
Other names:
JQ-1, JQ1
Contact us
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News alerts, weekly reports and conference planners
Associations
(27)
News
Trials
Company:
Roche
Drug class:
BET inhibitor
Related drugs:
‹
ABBV-744 (7)
ZEN-3694 (6)
INCB57643 (4)
BI 894999 (4)
SRA515 (3)
ABBV 075 (3)
GSK525762 (3)
GS-626510 (2)
PLX51107 (2)
DAK539 (2)
CPI-203 (1)
RG6146 (1)
ARCC-29 (0)
BET inhibitor (0)
CA2 (0)
CC-95775 (0)
EP31670 (0)
GSK1324726A (0)
INCB054329 (0)
JAB-8263 (0)
NHWD-870 (0)
ODM-207 (0)
OPN-2853 (0)
SF1126 (0)
SF2523 (0)
SF2535 (0)
ZEN-3219 (0)
ZEN003365 (0)
GS-5829 (0)
RVX 208 (0)
BMS-986158 (0)
BMS-986378 (0)
ABBV-744 (7)
ZEN-3694 (6)
INCB57643 (4)
BI 894999 (4)
SRA515 (3)
ABBV 075 (3)
GSK525762 (3)
GS-626510 (2)
PLX51107 (2)
DAK539 (2)
CPI-203 (1)
RG6146 (1)
ARCC-29 (0)
BET inhibitor (0)
CA2 (0)
CC-95775 (0)
EP31670 (0)
GSK1324726A (0)
INCB054329 (0)
JAB-8263 (0)
NHWD-870 (0)
ODM-207 (0)
OPN-2853 (0)
SF1126 (0)
SF2523 (0)
SF2535 (0)
ZEN-3219 (0)
ZEN003365 (0)
GS-5829 (0)
RVX 208 (0)
BMS-986158 (0)
BMS-986378 (0)
›
Associations
(27)
News
Trials
VERI cancer hierarchy
Reset Filters
MAF overexpression
Multiple Myeloma
MAF overexpression
Multiple Myeloma
JQ-1 + 10058-F4
Resistant: C3 – Early Trials
JQ-1 + 10058-F4
Resistant
:
C3
JQ-1 + 10058-F4
Resistant: C3 – Early Trials
JQ-1 + 10058-F4
Resistant
:
C3
EPCAM expression
Triple Negative Breast Cancer
EPCAM expression
Triple Negative Breast Cancer
JQ-1
Resistant: C3 – Early Trials
JQ-1
Resistant
:
C3
JQ-1
Resistant: C3 – Early Trials
JQ-1
Resistant
:
C3
SOX9 expression
Triple Negative Breast Cancer
SOX9 expression
Triple Negative Breast Cancer
JQ-1
Resistant: C3 – Early Trials
JQ-1
Resistant
:
C3
JQ-1
Resistant: C3 – Early Trials
JQ-1
Resistant
:
C3
GJA1 expression
Triple Negative Breast Cancer
GJA1 expression
Triple Negative Breast Cancer
JQ-1
Resistant: C3 – Early Trials
JQ-1
Resistant
:
C3
JQ-1
Resistant: C3 – Early Trials
JQ-1
Resistant
:
C3
CD24 expression
Triple Negative Breast Cancer
CD24 expression
Triple Negative Breast Cancer
JQ-1
Resistant: C3 – Early Trials
JQ-1
Resistant
:
C3
JQ-1
Resistant: C3 – Early Trials
JQ-1
Resistant
:
C3
BRD4 overexpression
Retinoblastoma
BRD4 overexpression
Retinoblastoma
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
MYCN amplification
Neuroblastoma
MYCN amplification
Neuroblastoma
JQ-1 + panobinostat
Sensitive: D – Preclinical
JQ-1 + panobinostat
Sensitive
:
D
JQ-1 + panobinostat
Sensitive: D – Preclinical
JQ-1 + panobinostat
Sensitive
:
D
MLL rearrangement
Leukemia
MLL rearrangement
Leukemia
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
P2RY8-CRLF2 fusion
B Acute Lymphoblastic Leukemia
P2RY8-CRLF2 fusion
B Acute Lymphoblastic Leukemia
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
MYC expression
Multiple Myeloma
MYC expression
Multiple Myeloma
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
JQ-1
Resistant: D – Preclinical
JQ-1
Resistant
:
D
JQ-1
Resistant: D – Preclinical
JQ-1
Resistant
:
D
KRAS Q61K
Non Small Cell Lung Cancer
KRAS Q61K
Non Small Cell Lung Cancer
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
KRAS G12S
Non Small Cell Lung Cancer
KRAS G12S
Non Small Cell Lung Cancer
JQ-1
Resistant: D – Preclinical
JQ-1
Resistant
:
D
JQ-1
Resistant: D – Preclinical
JQ-1
Resistant
:
D
KRAS G12V
Non Small Cell Lung Cancer
KRAS G12V
Non Small Cell Lung Cancer
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
KRAS mutation
Non Small Cell Lung Cancer
KRAS mutation
Non Small Cell Lung Cancer
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
MYCL overexpression
Multiple Myeloma
MYCL overexpression
Multiple Myeloma
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
FLT3 D835V
Acute Myelogenous Leukemia
FLT3 D835V
Acute Myelogenous Leukemia
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
FLT3 F691L
Acute Myelogenous Leukemia
FLT3 F691L
Acute Myelogenous Leukemia
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
GNAQ mutation
Uveal Melanoma
GNAQ mutation
Uveal Melanoma
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
BRAF V600E
Cutaneous Melanoma
BRAF V600E
Cutaneous Melanoma
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
GNA11 mutation
Uveal Melanoma
GNA11 mutation
Uveal Melanoma
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
PRC2 mutation
T Acute Lymphoblastic Leukemia
PRC2 mutation
T Acute Lymphoblastic Leukemia
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
FBXW7 underexpression
Breast Cancer
FBXW7 underexpression
Breast Cancer
JQ-1
Resistant: D – Preclinical
JQ-1
Resistant
:
D
JQ-1
Resistant: D – Preclinical
JQ-1
Resistant
:
D
FBXW7 underexpression
Breast Cancer
FBXW7 underexpression
Breast Cancer
JQ-1 + S63845
Sensitive: D – Preclinical
JQ-1 + S63845
Sensitive
:
D
JQ-1 + S63845
Sensitive: D – Preclinical
JQ-1 + S63845
Sensitive
:
D
CDKN2A deletion
Pancreatic Ductal Adenocarcinoma
CDKN2A deletion
Pancreatic Ductal Adenocarcinoma
palbociclib + JQ-1
Sensitive: D – Preclinical
palbociclib + JQ-1
Sensitive
:
D
palbociclib + JQ-1
Sensitive: D – Preclinical
palbociclib + JQ-1
Sensitive
:
D
FAT1 mutation
Squamous Cell Carcinoma of Head and Neck
FAT1 mutation
Squamous Cell Carcinoma of Head and Neck
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
BRD4 overexpression
Endometrial Cancer
BRD4 overexpression
Endometrial Cancer
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
JQ-1
Sensitive: D – Preclinical
JQ-1
Sensitive
:
D
^
^
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